Results 161 to 170 of about 16,639 (269)

Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy

Advanced Materials, EarlyView.
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla, Jacqueline J. Li, Qunzhou Zhang, Korey Patwari, Shihong Shi, Hannah M. Yamagata, Ryann A. Joseph, Briyanna N. Hymms, Sridatta V. Teerdhala, Emily Fitzgerald, Ori Z. Chalom, Kushol Gupta, Mohamad‐Gabriel Alameh, Drew Weissman, Anh D. Le, Michael J. Mitchell   +15 more
wiley   +1 more source

Service opening and wages of manufacturing firms: Evidence from China. [PDF]

Heliyon
Chen Y, Tang K, Lin Y, Xing J, Wang Z, Baoxian R.   +5 more
europepmc   +1 more source

The Impact of Big Data Management Capabilities on the Performance of Manufacturing Firms in Asian Economy During COVID-19: The Mediating Role of Organizational Agility and Moderating Role of Information Technology Capability. [PDF]

Front Psychol, 2022
Zhang J, Li H.
europepmc   +1 more source

A Geometrically Transient Platform for Bioelectronic Implants

Advanced Materials, EarlyView.
Minimally invasive bioelectronic implants often compromise performance for smaller sizes. To resolve this optimization dilemma, a wireless bioelectronic implant with a transient geometry is introduced (MiFi). The origami‐inspired device miniaturizes up to sixfold for syringe insertion and autonomously unfolds post‐implantation.
Selin Olenik, John D. Goodwin, Atharv Naik, Philip Coatsworth, Ioi Chit Cheung, Farbod Amirghasemi, Anies Sohi, Ehsan Abedi, Tayeb Tadlaoui, Maral P. S. Mousavi, Andriy S. Kozlov, Victoria Salem, Andrew S. Cowburn, Firat Guder   +13 more
wiley   +1 more source

The impact of the centralized volume-based procurement policy on Chinese pharmaceutical manufacturing firms' R&D investment: A difference-in-differences approach. [PDF]

PLoS One
Qiu F, Chen S, Li Y, Wang X, Zhu M.
europepmc   +1 more source

Resolving Heterogeneity of Targeted Lipid Nanoparticles Through Solution‐Based Biophysical Analyses

Advanced Materials, EarlyView.
AF4‐UV‐DLS‐MALS‐SAXS resolves previously inaccessible targeted lipid nanoparticle (tLNP) subpopulations that differ in size, shape, and composition. Correlation of subpopulation‐resolved biophysical properties with in vivo RNA delivery reveals that targeted placental transfection is associated with distinct tLNP subpopulations rather than ensemble ...
Hannah C. Geisler, Hannah C. Safford, Ajay S. Thatte, Marshall S. Padilla, Elisa Battistini, Hannah M. Yamagata, Violet M. Ullman, Alex Chan, Benjamin E. Nachod, Anushka Agrawal, Maxwell B. Watkins, Jesse B. Hopkins, Andrew Tsourkas, Kushol Gupta, Michael J. Mitchell   +14 more
wiley   +1 more source

Exploring Internet of Things adoption challenges in manufacturing firms: A Delphi Fuzzy Analytical Hierarchy Process approach. [PDF]

PLoS One
Shahriar H, Islam MS, Jahin MA, Ridoy IA, Prottoy RR, Abid A, Mridha MF.   +6 more
europepmc   +1 more source

Mechanically Robust and Depolymerizable Polyesters With Near‐Complete Monomer Recovery for Circular Additive Manufacturing

Advanced Materials, EarlyView.
A sustainable δ‐lactone‐based polymer platform enables multimodal additive manufacturing through DLP, DIW, and FFF, combining tunable crystallinity, photocurable networks, mechanical robustness, and functional response. The printed materials can be mechanically reprocessed and chemically depolymerized into recoverable monomers, demonstrating a closed ...
Farzad Gholami, Rampi Ramprasad, H. Jerry Qi   +2 more
wiley   +1 more source

Environmental taxes, technological innovation and firm performance: Evidence from China's manufacturing firms. [PDF]

Heliyon
Zhao A, Zhang H, Liu Y, Guan H.
europepmc   +1 more source