Results 101 to 110 of about 10,238,486 (293)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Poznańskie Studia Polonistyczne. Seria Literacka, 2010 The Library of the Poznań Society of Friends of Arts and Sciences has been recently enriched by the accession of the manuscript “Poetical texts from the first half of the nineteenth century”.
Joanna Pietrowicz
doaj +1 more source
, 2019 The study of modern manuscripts to examine writing processes is termed “genetic criticism.” A current trend that is sometimes overdramatized as “the archival turn” is a result of renewed interest in this discipline, which has a long tradition situated at the intersection between modern book history, bibliography, textual criticism, and scholarly ...
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Kuzey Azerbaycan'da Arapça Şiir Yazımı
Trabzon İlahiyat Dergisi, 2021 Arapçanın ilim, şiir ve iletişim dili olarak kullanıldığı bölgelerden birisi de Kuzey Azerbaycanʼdır. Bin yıldan fazla bir süre bölgede yaşamış âlim ve şâirler eserlerini bu dilde kaleme almışlarsa da bu çalışmaların büyük bir kısmı günümüze kadar yazma ...
Kamran Abdullayev
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Chapter Lothar’s manuscripts, manuscripts for Lothar, manuscripts of Lothar’s time [PDF]
, 2022 This paper aims to give an account of some of the manuscripts related to Lothar. In its first section an attempt is made at retracing a set of books that could have belonged to Lothar’s library, nowadays known only from secondary sources. In the second section some display codices are discussed, either commissioned by Lothar, or dedicated to him, such ...
openaire +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source