Results 181 to 190 of about 6,428,242 (364)
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
First trimester prediction of gestational diabetes mellitus by machine learning in twin pregnancies. [PDF]
Louzoun Y +23 more
europepmc +1 more source
[Recensão a] RAMSEY, Frank Plumpton. On Truth . Original Manuscript Materiais (1927-1929) froco lhe Ramsey Collection at the University of Pittsburgh edited by Nicholas Rescher and Ulrich Majer. (Episteme, vol. 16) [PDF]
António Manuel Martins
openalex
Karoline Mortensen, T. Hughes
semanticscholar +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Ulcerated necrobiosis lipoidica: clinical and histopathological presentation of two cases. [PDF]
Giriboni VM +3 more
europepmc +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source

