Results 241 to 250 of about 12,863,015 (313)

Taking stock: Can captive species contribute to biodiversity conservation? [PDF]

PLoS One
Lennon JJ, Pernetta AP, White RL, Crooks N.   +3 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Rapid clinical improvement with upadacitinib in genetically confirmed Hailey-Hailey disease after adalimumab failure. [PDF]

An Bras Dermatol
Akşan B, Akay EB, Kundakcı Akay E.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Mapping the national burden of cellulitis and related conditions in the United States, 1999-2024: a retrospective cohort analysis. [PDF]

Ann Med Surg (Lond)
Altamimi A, Mohammed Dahi A, ALJohani YS, Alharbi W, Saud Alharbi A, Aldousari AMHM, Almutairi AG, Alenezi AI, Alrashidi SJSAA, Alanazi AAN, Alolyan AM, Kumar L, Raja A, Chaulagain A.   +13 more
europepmc   +1 more source

Standardised proformas for the management of hypodontia patients: A new standard for clinical documentation. [PDF]

J Orthod
Johal A, Wong F, Shahdad S, Dean R, Worthington S.   +4 more
europepmc   +1 more source

Increased risk of corneal transplant rejection following SARS-CoV-2 infection and vaccination. [PDF]

Int Ophthalmol
Allen NE, Niederer RL, Gokul A, Zhang J, Casey A, Tippett G, McGhee CNJ.   +6 more
europepmc   +1 more source

Evaluating the acceptability, feasibility, and implementation fidelity of a multipurpose mobile health (mHealth) app used for Tuberculosis (TB) contact tracing by Ward-Based Outreach Teams (WBOTs) in South Africa. [PDF]

PLOS Glob Public Health
Mudzengi DL, Tsope L, Hippner P, Mboniswa F, Mpanza T, Dube T, Lessells R, Govender I, Gumede D, Grant AD, Fielding K, Chetty-Makkan CM, Velen K, Charalambous S.   +13 more
europepmc   +1 more source

From Naltrexone Induction to Response-Guided Care in Alcohol-Associated Cirrhosis. [PDF]

Liver Int
Mao X, Hu X.
europepmc   +1 more source