Results 161 to 170 of about 41,814,003 (312)

Dental aesthetic self-perception, smile satisfaction and associated factors among adults: A cross-sectional study. [PDF]

open access: yesPLoS One
Baig J   +7 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Basel, Universitätsbibliothek, O II 29 : Hincmarus Remensis

open access: yes
Early modern composite manuscript containing the only manuscript textual witnesses for several writings by archbishop Hincmar of Reims (845-882), for example for the treatise De ordine palatii, important for the constitutional history of the Carolingian ...
Fäsch, Ruman, Hincmarus, Remensis
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Frauenfeld, Kantonsbibliothek Thurgau, Y 114 : Chronicle of Selnau Abbey

open access: yes
Chronicle of Selnau Abbey by Heinrich Murer (1588-1638, from 1614 on a Conventual at the Carthusian Monastery of Ittingen). This incomplete manuscript would have treated the Cistercian monasteries of Switzerland in a first part and, in a second more ...
Murer, Heinrich
core   +1 more source

Electronic Media And Its Role In The Dissemination Of Arabic Manuscript Heritage. An Analytical Study Of The Facebook Page, Arabic Manuscript Gallery.

open access: yesThe Journal of Studies in Language, Culture and Society
The modern technological revolution has produced a modern media style that differs in its characteristics, form and content from traditional media. It mainly relies on the information network or the Internet, which has given it unprecedented updates and
Latifa Nessighaoui
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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