Results 61 to 70 of about 1,514,054 (297)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Features first translation confucian text “Lunyu” on russian language
This paper is about research of the manuscript “Book Sishu or Shang Lunyu, of Chinese confucianistic law. Translated by Jacob Volkov”. This manuscript is a first Russian translation of confucianistic “Analects”, made in the XVIIIth century.
D. V. Tsvetkov
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Catalogue of Turkish Manuscripts in the Library of Leiden University and Other Collections in the Netherlands [PDF]
The present catalogue is the fourth and final volume in a series that covers the Turkish manuscripts preserved in public libraries and museums in the Netherlands.
Schmidt, Jan
core +3 more sources
Is the Chuu Silk Manuscript a Chuu manuscript?
The Chuu Silk Manuscript, known to the scholarly community since the 1950s, was until the manuscript discoveries of the past three decades one of the few extant exemplars of pre-Hann Chinese manuscripts. Because it was found in the area of the ancient state of Chuu and is in its physical appearance and contents very distinctive, incorporating both text
openaire +2 more sources
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
An edition of 'Contemplations of the dread and love of God' [PDF]
This thesis presents an edition of Contemplations of the Dread and Love of God, a late Middle English devotional prose text for which no critical edition is currently available.
Connolly, Margaret
core +2 more sources

