Advanced Science, EarlyView.The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob +12 more
wiley +1 more source
Evaluating generative AI tools for visual communication design using the CoCoSo method under interval valued spherical fuzzy environment. [PDF]
Sci RepSun H, Liu S.
europepmc +1 more source
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
Postfeminist Healthism: Understanding the Gendering of Healthism Using Menstrual Tracking Apps as an Example. [PDF]
Sociol Health IllnRiley S, Evans A, Robson M.
europepmc +1 more source
XOR‐Logic Phase Coding Programmable Metasurface for Low Power‐Consumption Systems
Advanced Science, EarlyView.By leveraging XOR logic, the biasing‐network complexity of 2D programmable metasurfaces is reduced from m×n to m+n through efficient row‐column control. This enables versatile functions including beam deflection and beamforming, facilitating applications in wireless communications and beyond.
Ruichao Zhu +10 more
wiley +1 more source
Goal-directed actions and habits in head-fixed mice. [PDF]
Front Behav NeurosciManusky LM +6 more
europepmc +1 more source
Vacancy‐Suppressed Garnet Electrolytes for Durable Solid‐State Batteries
Advanced Science, EarlyView.A Li/O‐rich sintering strategy effectively suppresses intrinsic lithium and oxygen vacancies in cubic garnet electrolytes, yielding a dense and stable microstructure. The vacancy‐controlled electrolyte exhibits enhanced interfacial and air stability, enabling long‐term solid‐state battery cycling and providing a general design principle for defect ...
Seokjae Hong +20 more
wiley +1 more source
A Dynamic Hybrid Weighting Framework for Teaching Effectiveness Evaluation in Multi-Criteria Decision-Making: Integrating Interval-Valued Intuitionistic Fuzzy AHP and Entropy Triggering. [PDF]
Entropy (Basel)Lu C, Zhang Y.
europepmc +1 more source
Advanced Science, EarlyView.The RNA G‐quadruplexes formed at the 5'‐end of the RNA component of human telomerase possess extreme slow unfolding rate, rendering them resistant to nuclease degradation. The helicase DHX36 overcame this kinetic barrier and significantly reduced the folded fraction.
Qun Luo +5 more
wiley +1 more source