Results 41 to 50 of about 65,929 (299)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Approximating Propositional Calculi by Finite-valued Logics [PDF]

open access: yes, 1994
The problem of approximating a propositional calculus is to find many-valued logics which are sound for the calculus (i.e., all theorems of the calculus are tautologies) with as few tautologies as possible.
Baaz, Matthias, Zach, Richard
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

On MV-Algebraic Versions of the Strong Law of Large Numbers

open access: yesEntropy, 2019
Many-valued (MV; the many-valued logics considered by Łukasiewicz)-algebras are algebraic systems that generalize Boolean algebras. The MV-algebraic probability theory involves the notions of the state and observable, which abstract the probability ...
Piotr Nowak, Olgierd Hryniewicz
doaj   +1 more source

A Scoping Review on Artificial Intelligence–Supported Interventions for Nonpharmacologic Management of Chronic Rheumatic Diseases

open access: yesArthritis Care &Research, EarlyView.
This review summarizes artificial intelligence (AI)‐supported nonpharmacological interventions for adults with chronic rheumatic diseases, detailing their components, purpose, and current evidence base. We searched Embase, PubMed, Cochrane, and Scopus databases for studies describing AI‐supported interventions for adults with chronic rheumatic diseases.
Nirali Shah   +5 more
wiley   +1 more source

A study of fuzzy and many-valued logics in cellular automata

open access: yes, 2007
In this paper we provide an analytical study of the theory of multi-valued and fuzzy cellular automata where the fuzziness appears as the result of the application of an underlying multi-valued or continuous logic as opposed to standard logic as used ...
Mingarelli, Angelo B.
core   +3 more sources

Validation of the Pediatric Arthritis Ultrasound Scoring System for the Elbow, Wrist, and Finger Joints in Children with Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, Accepted Article.
Objective We aimed to validate the Pediatric Arthritis Ultrasound Scoring System (PAUSS) for upper extremity joints in children with juvenile idiopathic arthritis (JIA). Methods Children with JIA were evaluated for elbow, wrist, or finger arthritis by clinical examination (CE) and musculoskeletal ultrasound (MSUS) with images scored according to the ...
Patricia Vega‐Fernandez   +12 more
wiley   +1 more source

Hopfield Neural Networks for Online Constrained Parameter Estimation With Time‐Varying Dynamics and Disturbances

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
This paper proposes two projector‐based Hopfield neural network (HNN) estimators for online, constrained parameter estimation under time‐varying data, additive disturbances, and slowly drifting physical parameters. The first is a constraint‐aware HNN that enforces linear equalities and inequalities (via slack neurons) and continuously tracks the ...
Miguel Pedro Silva
wiley   +1 more source

Many-Valued Logics and Translations

open access: yesJournal of Applied Non-Classical Logics, 1999
This work presents the concepts of translation and conservative translation between logics. By using algebraic semantics we introduce several conservative translations involving the classical propo...
D'Ottaviano, Ítala M. Loffredo   +1 more
openaire   +3 more sources

Many-valued hybrid logic [PDF]

open access: yesJournal of Logic and Computation, 2015
In this paper we define a many-valued semantics for hybrid logic and we give a sound and complete tableau system which is proof theoretically well-behaved, in particular, it gives rise to a decision procedure for the logic. This shows that many-valued hybrid logics is a natural enterprise and opens up the way for future applications.
Hansen, Jens Ulrik   +2 more
openaire   +2 more sources

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