Results 191 to 200 of about 15,152,741 (289)

"Learning to Live Without Him in My Home When a Piece of My Heart Went with Him": End-of-Life Decision-Making Experiences of Companion Animal Caregivers. [PDF]

Animals (Basel)
Kogan LR, Currin-McCulloch J, Jafarian S, Klein E, Cooney K.   +4 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Excitons make quantum leap in just 2.5 femtoseconds. [PDF]

Light Sci Appl
Neufeld O.
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Overcoming Metacognitive Bias: What Surgeons Can Learn From Athletes. [PDF]

Ann Surg Open
Acker RC, Hashimoto DA, Kelz RR.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Many-eyes and sentinels in selfish and cooperative groups. [PDF]

Proc Natl Acad Sci U S A
Pilgrim C, Bate AM, Sigalou A, Aellen M, Morford J, Warren E, Krupenye C, Biro D, Mann RP.   +8 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Thrombophilias and adverse pregnancy outcome

Haematologica, 2003
A Many, MJ Kupferminc
doaj  

In Memory of Professor Charles Mayaud. [PDF]

Ann Intensive Care
Fartoukh M.
europepmc   +1 more source