Results 101 to 110 of about 1,018,353 (274)

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

open access: yesAdvanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin   +17 more
wiley   +1 more source

O movimento da auto-organização e os seus contributos para a educação [PDF]

open access: yes, 2013
O artigo contextualiza historica e epistemologicamente o surgimento do movimento da auto-organização (MAO), avançando depois para a sua explicação como corrente epistemológica, diferenciada de outras correntes suas contemporâneas.
Oliveira, Clara Costa
core  

Disulfide‐Bridged Ru Complex–Mediated Photo‐Disulfidptosis for Colorectal Cancer Therapy

open access: yesAdvanced Science, EarlyView.
In this work, a binuclear ruthenium complex, RuSSRu was developed for efficient colorectal cancer (CRC) treatment. The synergistic interaction between disulfidptosis and lysosomal damage‐induced apoptosis induced by RuSSRu amplified tumor cell death. This innovative approach offers a potent therapeutic strategy for CRC.
Simeng He   +8 more
wiley   +1 more source

New Trends in UV Curing

open access: yesEurasian Chemico-Technological Journal, 2004
We present an overview of the use of photochemistry applied to polymerization and crosslinking reactions by radical or cationic process used for thin film technologies and more generally for coatings.
Marc J.M. Abadie, Vanda Yu. Voytekunas
doaj   +1 more source

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

open access: yesAdvanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li   +12 more
wiley   +1 more source

Experimental investigation on dynamic behaviour of heavy-haul railway track induced by heavy axle load

open access: yesTransport, 2019
The damage to the track structure and the influence to the line deformation have greatly deteriorated with the increase of the axle load compared with that of the ordinary trains.
Zhiyong Shi   +5 more
doaj   +1 more source

Immobilizzazione dell'enzima monoamminossidasi di tipo A (MAO-A) e studio della sua attivita catalitica [PDF]

open access: yes, 2008
La monoammino ossidasi (MAO) è un enzima localizzato nella membrana mitocondriale esterna e distribuito in vari tessuti. La MAO catalizza la deamminazione ossidativa di ammine primarie, secondarie e terziarie; in questo processo enzimatico, la porzione ...
MARTELLI, TOMMASO
core  

Comment on "Experimental determination of superconducting parameters for the intermetallic perovskite superconductor MgCNi$_3$"

open access: yes, 2003
In a recent paper (Phys. Rev. {\bf B 67}, 094502 (2003)) Mao et al. investigated the bias-dependent conductance of mechanical junctions between superconducting MgCNi$_3$ and a sharp W tip.
B.I. Verkin   +11 more
core   +1 more source

Stabilization of Single Metal Atoms on Graphitic Carbon Nitride: Synthetic Strategies and Emerging Applications

open access: yesAdvanced Science, EarlyView.
This review highlights recent advancements in stabilizing single metal atoms on graphitic carbon nitride emphasizing innovative synthesis strategies and emerging applications in electrocatalysis, photocatalysis and organic transformations, along with key challenges and future perspective. Abstract Emerging as a new frontier in catalysis science, single‐
Wenyao Zhang   +6 more
wiley   +1 more source

Development and evaluation of a medicine-food homology herbal tea for anti-heat stroke efficacy and antioxidant activity

open access: yesFood, Nutrition and Health
Heat stroke (HS) is a life-threatening condition with limited preventive options. Inspired by the classical Qingshu Yiqi Decoction, this study developed a palatable health tea Xiao Qingshu Yiqi Decoction (XQYD) using exclusively medicine-food homology ...
Hanfei Wang   +8 more
doaj   +1 more source

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