Results 161 to 170 of about 1,018,353 (274)

Unveiling a New Link: Cholesterol Deficiency in Smith–Lemli–Opitz and Niemann–Pick C as a Driver of Ciliopathies

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson, Maria Teresa Fiorenza   +1 more
wiley   +1 more source

Design, synthesis and biological evaluation of novel 3,4-dihydro-2(1<i>H</i>)-quinoline-<i>O</i>-carbamate derivatives as AChE/MAO-B dual inhibitors for the treatment of Alzheimer's disease. [PDF]

RSC Med Chem
Fu W, Wang K, Chen H, Liu T, Liu X, Jin Q, Tan Z, Dong W, Liu W, Sang Z.   +9 more
europepmc   +1 more source

Methylophiopogonanone a attenuates pulmonary fibrosis by inhibiting SPP1‐mediated macrophage polarization via the PI3K/Akt pathway

Animal Models and Experimental Medicine, EarlyView.
Transcriptome sequencing identified secreted phosphoprotein 1 (SPP1) as a crucial target through which methylophiopogonanone A (MOA) ameliorates pulmonary fibrosis. Molecular docking and microscale thermophoresis (MST) assays confirmed a favorable binding affinity between MOA and SPP1.
Fan Yang, Tian Li, Weiran Jia, Dingjie Xu, Liangdan Sun, Yanlei Ge, Yiwei Shi, Hong Xu, Xudong Song, Fuyu Jin, Na Mao   +10 more
wiley   +1 more source

Morpholine as a privileged scaffold for neurodegenerative disease therapeutics. [PDF]

RSC Adv
Parmbil SK, Kumar S, Rangarajan TM, Grace Thomas Parambi D, Maliyakkal N, Petzer A, Petzer JP, Mathew B.   +7 more
europepmc   +1 more source

Selenium Nanomaterials for Wound Healing: Synergistic Strategies from Anti‐Infection to Tissue Regeneration

Advanced NanoBiomed Research, EarlyView.
Selenium nanoparticles (SeNPs) are emerging as multifunctional platforms for wound healing, integrating antimicrobial, anti‐inflammatory, and proregenerative activities. This review summarises key mechanisms and recent advances in SeNP‐enabled composite dressings, immunomodulatory nanocomposites, microenvironment‐responsive hydrogels, photothermal and ...
Yangxia Chen, Xiaoshuang Liang, Sirui Li, Shuoshan Li, Wei Liu, Yingping Lin, Siqi Li, Zehang Zhang, Judun Zheng, Tianfeng Chen, Rongyi Chen   +10 more
wiley   +1 more source

Correction: Reducing assessment timing in Tap-Test-positive patients with iNPH: a 24-hour strategy and the exploratory role of the Symbol-Digit Modalities Test in surgical triage. [PDF]

Fluids Barriers CNS
Yang Z, Geng Z, Yin R, Deng C, Sun S, Li P, Chen Y, Liu X, Fang Z, Wang Y, Zhang X, Dong L, Mao C, Gao J, Wei J.   +14 more
europepmc   +1 more source

Preparation and Characterization of Oxide Coatings with LDH Nanosheets on AZ91 Magnesium Alloy by a One-Step Low Voltage Microarc Oxidation Process. [PDF]

Materials (Basel)
Shi L, Lu X, Li P, Liu C, Liang J.
europepmc   +1 more source

Correction for Lan et al., "Small Interfering RNA Pathway Modulates Initial Viral Infection in Midgut Epithelium of Insect after Ingestion of Virus". [PDF]

J Virol
Lan H, Chen H, Liu Y, Jiang C, Mao Q, Jia D, Chen Q, Wei T.   +7 more
europepmc   +1 more source

Correction: A systematic review and exploration of clinical application of Liver depression syndrome in breast cancer. [PDF]

Front Oncol
Wu P, Mao S, Zuo Q, Guo Q, Chen Q.
europepmc   +1 more source

Creation of a Pseudotsuga menziesii nucellus cell suspension culture system to produce proteins involved in reproduction

Applications in Plant Sciences, EarlyView.
Abstract Premise Cell suspension cultures of Douglas‐fir (Pseudotsuga menziesii) nucellus were created to overcome phenological limitations to the in situ study of bioactive proteins within and secreted by nucellar cells. Methods Proteins isolated from the cell suspension culture medium were analyzed using mass spectrometry, as were Douglas‐fir post ...
Andrea Coulter, YuQi Li, Julia Lakhani, Natalie Prior, Patrick von Aderkas   +4 more
wiley   +1 more source