Results 11 to 20 of about 1,378,682 (321)
Frontiers in Bioengineering and Biotechnology, 2023 Titanium (Ti) and its alloys have good biocompatibility, mechanical properties and corrosion resistance, making them attractive for biomedical applications.
Xueying Wen +4 more
semanticscholar +1 more source
ACS Omega, 2023 Thirteen isopropyl chalcones (CA1–CA13) were synthesized and evaluated for their inhibitory activity against monoamine oxidase (MAO). All compounds inhibited MAO-B more effectively than MAO-A. Compound CA4 most potently inhibited MAO-B with an IC50 value
S. Sushanth Kumar +9 more
semanticscholar +1 more source
A critical appraisal of MAO-B inhibitors in the treatment of Parkinson’s disease
Journal of neural transmission, 2022 Since the 1980s, the MAO-B inhibitors have gained considerable status in the therapy of the Parkinson’s disease. In addition to the symptomatic effect in mono- and combination therapies, a neuroprotective effect has repeatedly been a matter of some ...
W. Jost
semanticscholar +1 more source
Redefining differential roles of MAO-A in dopamine degradation and MAO-B in tonic GABA synthesis
Experimental and Molecular Medicine, 2021 Monoamine oxidase (MAO) is believed to mediate the degradation of monoamine neurotransmitters, including dopamine, in the brain. Between the two types of MAO, MAO-B has been believed to be involved in dopamine degradation, which supports the idea that ...
Hyun-U Cho +7 more
semanticscholar +1 more source
Monoamine Oxidase (MAO) as a Potential Target for Anticancer Drug Design and Development
Molecules, 2021 Monoamine oxidases (MAOs) are oxidative enzymes that catalyze the conversion of biogenic amines into their corresponding aldehydes and ketones through oxidative deamination.
Reem Aljanabi +5 more
semanticscholar +1 more source
Exploration of Clinical Breakpoint of Danofloxacin for Glaesserella parasuis in Plasma and in PELF
Antibiotics, 2021 Background: In order to establish the clinical breakpoint (CBP) of danofloxacin against G. parasuis, three cutoff values, including epidemiological cutoff value (ECV), pharmacokinetic-pharmacodynamic (PK-PD) cutoff value (COPD) and clinical cutoff value (
Zihui Xu +11 more
doaj +1 more source
The application of compaction device for highway structural layer in the road construction of Yun-Mao Highway [PDF]
E3S Web of Conferences, 2021 The compaction device for highway structural layer is the hinge connection of the end of the hydraulic breaker rod of a conventional excavator and the base of a compaction device.
He Boqian, Lou Jian
doaj +1 more source
Nature Communications, 2020 The antiandrogen enzalutamide (Enz) has improved survival in castration resistant prostate cancer (CRPC) patients. However, most patients eventually develop Enz resistance that may involve inducing the androgen receptor (AR) splicing variant 7 (ARv7 ...
Ke-liang Wang +14 more
semanticscholar +1 more source
Platelet monoamine oxidase activity in alcoholics with and without a family history of alcoholism [PDF]
, 2000 A number of studies point at platelet monoamine oxidase (MAO) activity being reduced in alcoholics with a family history of drinking, this being a possible vulnerability marker for alcoholism.
Benda, Ellen +5 more
core +1 more source
Pharmaceutics, 2021 Zoonotic intestinal pathogens threaten human health and cause huge economic losses in farming. Enrofloxacin (ENR) shows high antibacterial activity against common intestinal bacteria.
Kaixiang Zhou +7 more
doaj +1 more source