Results 231 to 240 of about 6,226,885 (278)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Vectorized Agrivoltaics Dataset in China from 2010 to 2022. [PDF]

Sci Data
Zhang X, Ma X.
europepmc   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Influences and Training Strategies for Effective Object Detection in Challenging Environments Using YOLO NAS-L. [PDF]

Sensors (Basel)
Steindl G, Baca A, Kornfeind P.
europepmc   +1 more source

Study protocol: MRI-based assessment of cerebral blood flow under pharmacologically elevated blood pressure in patients under general anesthesia, and in sedated ICU patients with aneurysmal subarachnoid hemorrhage. [PDF]

PLoS One
Österlind J, Birnefeld J, Birnefeld E, Hultin M, Qvarlander S, Wåhlin A, Holmlund P, Zarrinkoob L.   +7 more
europepmc   +1 more source

PBZGNet: A Novel Defect Detection Network for Substation Equipment Based on Gradual Parallel Branch Architecture. [PDF]

Sensors (Basel)
Hu M, Zhuang Y, Wang J, Hu Y, Sun D, Xu D, Zhai Y.   +6 more
europepmc   +1 more source

An interactive dashboard for global reports on the Ralstonia solanacearum species complex. [PDF]

Access Microbiol
Elmgreen VN, Ramirez B, Sharma R, Vinatzer BA, Lowe-Power TM, Pierce-Ward NT.   +5 more
europepmc   +1 more source

Evaluation of the reproducibility and performance characteristics of the Phagomagnetic separation-qPCR assay for rapidly detecting viable <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> in bovine milk and feces. [PDF]

Front Vet Sci
Grant IR, Sevilla IA, Molina E, Romero Martinez B, Lorente-Leal V, Thibault-Poisson VC, Cechova M, Köhler H.   +7 more
europepmc   +1 more source