Results 201 to 210 of about 16,648,047 (271)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

GCEA-YOLO: An Enhanced YOLOv11-Based Network for Smoking Behavior Detection in Oilfield Operation Areas. [PDF]

Sensors (Basel)
Liu Q, Wan X, Sheng Y, Wang S, Wei B.
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Comparing voice-only navigation and paper maps in middle-aged and older adults: A randomized crossover field study of wayfinding, mood, usability, and text-mined user experiences. [PDF]

Sci Rep
Nagata C, Ota T, Sumida Y, Isomura Y, Shimizu Y, Yamamoto T, Chen C.   +6 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Comparison of a mean arterial pressure alarm to the hypotension prediction index in preventing intraoperative hypotension in elective moderate- to high-risk non-cardiac surgical patients: a study protocol for a blinded, parallel, randomized controlled trial with a non-inferiority framework. [PDF]

Trials
Mulder MP, Florax AA, Harmannij-Markusse M, Fresiello L, Donker DW, Potters JW.   +5 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

An integrated framework for multi-feature fusion and intelligent recognition of design elements: Challenges and solutions. [PDF]

PLoS One
Wenbo L.
europepmc   +1 more source

Letter to the Editor Regarding 'Profile of Metabolic Dysfunction-Associated Steatotic Liver Disease: Mapping Across Different Indian Populations (MAP Study)'. [PDF]

Diabetes Ther
Bose R, Sridharan K, Gupta R.
europepmc   +1 more source

Lightweight robust detection of anthropogenic floating debris in turbid and dynamic aquatic environments via enhanced feature fusion. [PDF]

Sci Rep
Zhong Y, Wan J, Cao M, Tan Z, Qiu Y, Zhang L, Ji X, Shen L, Yang T.   +8 more
europepmc   +1 more source