Results 71 to 80 of about 16,648,047 (271)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Information System Design Map Data Search in PT. Amoseas Indoensia [PDF]
Availability of data at the time it takes has to be the key success of the course of anactivity. This also applies to a mining company such as the PT. Amoseas IndonesiaInc..
Drs. Eko Hadiyanto, MM Drs. Eko Hadiyanto, MM +1 more
core
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Uncertainty, learning design, and interdisciplinarity: systems and design thinking in the school classroom [PDF]
This paper explores aspects of learning design for design thinking within a small (circa 100) remote rural secondary (12-18 year old) school in the Highlands of Scotland.
Macintyre, Ronald
core
Map++: A Crowd-sensing System for Automatic Map Semantics Identification
Digital maps have become a part of our daily life with a number of commercial and free map services. These services have still a huge potential for enhancement with rich semantic information to support a large class of mapping applications. In this paper,
Aly, Heba +2 more
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Som Based Assurance Assessment for Information Security Management System in Organization [PDF]
Information Security Management System (ISMS) has a lot of standards such as ISO/IEC 27001. In order to assess the quality assurance of ISMS, an organization should design and implement some mechanism.
Akhriza, T. M. (Tubagus)
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source

