Results 81 to 90 of about 485,746 (283)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Extending generalized Whitney maps [PDF]
Archivum Mathematicum, 2017 For metrizable continua, there exists the well-known notion of a Whitney map. If X is a nonempty, compact, and metric space, then any Whitney map for any closed subset of 2X can be extended to a Whitney map for 2X [3, 16.10 Theorem]. The main purpose of this paper is to prove some generalizations of this theorem.
openaire +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Generalized convex set-valued maps
Journal of Mathematical Analysis and Applications, 2003 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Benoist, Joël, Popovici, Nicolae
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Cartographic Line Generalization Based on Radius of Curvature Analysis
ISPRS International Journal of Geo-Information, 2018 Cartographic generalization is one of the important processes of transforming the content of both analogue and digital maps. The process of reducing details on the map has to be conducted in a planned way in each case when the map scale is to be reduced.
Bogdan Kolanowski +2 more
doaj +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Method of Constructing Point Generalization Constraints Based on the Cloud Platform
ISPRS International Journal of Geo-Information, 2018 As an important part of spatial data, the point feature has always been an essential element in web maps and navigation maps. With the development of location-based services and the rapid increase in volunteered geographic information and social media ...
Jiemin Zhou +5 more
doaj +1 more source