Results 51 to 60 of about 161,455 (261)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Automatic Room Segmentation of 3D Laser Data Using Morphological Processing
In this paper, we introduce an automatic room segmentation approach based on morphological processing. The inputs are registered point-clouds obtained from either a static laser scanner or a mobile scanning system, without any required prior information ...
Jaehoon Jung +2 more
doaj +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Light microscopy based approach for mapping connectivity with molecular specificity
Mapping neuroanatomy is a foundational goal of connectomics, and the gold standard method is electron microscopy as light microscopy lacks nanoscale resolution.
Fred Y. Shen +5 more
doaj +1 more source
Trajectory-Based Dynamic Map Labeling [PDF]
In this paper we introduce trajectory-based labeling, a new variant of dynamic map labeling, where a movement trajectory for the map viewport is given. We define a general labeling model and study the active range maximization problem in this model. The problem is NP-complete and W[1]-hard.
Andreas Gemsa +2 more
openaire +3 more sources
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Navigationssysteme, beziehungsweise digitale Kartenapps, haben sich zu alltäglichen Begleitern entwickelt. Waren digitale Karten vor einem Jahrzehnt ein wertvolles Gut - Updates für Navigationssysteme wurden für viel Geld verkauft- sind sie heute durch die Verbreitung von Google Maps und Co. eine Selbstverständlichkeit.
openaire +3 more sources
An Algorithmic Framework for Labeling Road Maps [PDF]
Given an unlabeled road map, we consider, from an algorithmic perspective, the cartographic problem to place non-overlapping road labels embedded in their roads. We first decompose the road network into logically coherent road sections, e.g., parts of roads between two junctions. Based on this decomposition, we present and implement a new and versatile
Benjamin Niedermann, Martin Nöllenburg
openaire +3 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source

