Results 141 to 150 of about 1,358,257 (368)

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

ClinicalLINKS Project within DDSWQ Medicare Local

International Journal of Integrated Care, 2014
Shirley-Anne Lee Gardiner, Tiana Gurney
doaj   +3 more sources

Essential tuberculosis medicines and health outcomes in countries with a national essential medicines list

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2022
Background: Tuberculosis (TB) remains a major cause of morbidity and mortality globally despite effective treatments. Along with high-quality health services, essential medicines are a key tool in curbing TB related mortality.
Darshanand Maraj, Liane Steiner, Nav Persaud   +2 more
doaj  

Campaign to revitalise academic medicine: A road map needs to be drawn for the 21st century [PDF]

, 2004
Jean D. Gray
openalex   +1 more source

Curriculum mapping for Focused Acute Medicine Ultrasound (FAMUS)

Acute Medicine Journal, 2018
Dear sir/madam, Point of care ultrasound (POCUS) in the hands of the non-radiologist has seen a steady growth in popularity amongst emergency, intensive care and acute medical physicians. Increased accessibility to portable, purpose-built ultrasound machines has meant that clinicians often have access to a safe and non-invasive tool to enhance their ...
Andrew Walden, Nicholas Smallwood, P Lawrenson, Jennie Stephens, K F Alber, A Gilmore, Martin Dachsel, Eugene Tabiowo, R Matsa   +8 more
openaire   +4 more sources

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Validation study of health administrative data algorithms to identify individuals experiencing homelessness and estimate population prevalence of homelessness in Ontario, Canada

BMJ Open, 2019
Objectives To validate case ascertainment algorithms for identifying individuals experiencing homelessness in health administrative databases between 2007 and 2014; and to estimate homelessness prevalence trends in Ontario, Canada, between 2007 and 2016 ...
Lucie Richard, Stephen W Hwang, Cheryl Forchuk, Rosane Nisenbaum, Kristin Clemens, Kathryn Wiens, Richard Booth, Mahmoud Azimaee, Salimah Z Shariff   +8 more
doaj   +1 more source

Epidemiology Competencies and Preventive Medicine Residencies: Do They Mix and Map? [PDF]

, 2008
Matthew L. Boulton, JoLynn P. Montgomery, Angela J. Beck   +2 more
openalex   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Map of Medicine: A change management tool for integration of local health services

International Journal of Integrated Care, 2014
Amanda Hese, Erin Lilley, Jennifer Pollock   +2 more
doaj   +3 more sources