Results 241 to 250 of about 166,920,662 (304)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Towards a clinically practical computational platform for systematically adapting radiation therapy for glioma patients. [PDF]

Phys Med Biol
Miniere HJM, Hormuth DA, Lima EABF, Whitaker TJ, Farhat M, Panthi B, Langshaw H, Shanker MD, Talpur W, Thrower S, Goldman J, Chung C, Yankeelov TE.   +12 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Remimazolam Versus Propofol for Anesthesia with I-Gel Airway Management During Coil Embolization of Unruptured Intracranial Aneurysms: A Randomized Controlled Trial. [PDF]

J Clin Med
Oh J, Park SY, Heo JY, Park MS, Joe HB.
europepmc   +1 more source

Beyond the numbers: hypotension, algorithms, and the elusive promise of renal protection. [PDF]

Ann Transl Med
da Hora Passos R, Melo RH, Rabello Filho R, Zawadzki B, Hamzaoui O.   +4 more
europepmc   +1 more source

Exploratory Hemodynamic and Hematologic Trajectories by Culture Status Among Neonates Evaluated for Infection. [PDF]

Children (Basel)
Rotea A, Rotea B, Meche VA, Suba M, Roșca O, Cerbu B, Enătescu I, Dima MA, Iacob ER, Gluhovschi A, Iacob D.   +10 more
europepmc   +1 more source

MAPPING OFGLOBALFORENSIC MEDICINE RESEARCH

openaire   +1 more source

Efficacy and safety of preoperative intranasal dexmedetomidine in adults: a systematic review and meta-analysis of randomized controlled trials. [PDF]

Braz J Anesthesiol
Voznyy V, Elganga M, Tawfik L, Tan T, Yu S, Yan E, Saripella A, Englesakis MF, Chung F.   +8 more
europepmc   +1 more source

MAP-Derived Shock Index for Point-of-Care Physiological Risk Stratification After CT-Confirmed Cervical Spine Fracture: Development and Internal Validation of a Prognostic Model for In-Hospital Mortality. [PDF]

Diagnostics (Basel)
Pepele MS, Karataş Ayhan M, Derya S, Murat M, Gürbüz Ş, Yücel N.   +5 more
europepmc   +1 more source

Monitoring of cerebral autoregulation during major surgery in adults, including cardiac surgery: mechanisms, anesthetic impacts, and clinical applications. [PDF]

Front Med (Lausanne)
Gao B, Alwesabi AK, Yang B, Xie J, Li F, Su X, Liu Q, Liu Y, Fu Q, Ji C, Gao Z, Xie J, Liu Y.   +12 more
europepmc   +1 more source