Results 51 to 60 of about 1,443,694 (284)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Contribution of high risk groups’ unmet needs may be underestimated in epidemic models without risk turnover: A mechanistic modelling analysis

Infectious Disease Modelling, 2020
Background: Epidemic models of sexually transmitted infections (STIs) are often used to characterize the contribution of risk groups to overall transmission by projecting the transmission population attributable fraction (tPAF) of unmet prevention and ...
Jesse Knight, Stefan D. Baral, Sheree Schwartz, Linwei Wang, Huiting Ma, Katherine Young, Harry Hausler, Sharmistha Mishra   +7 more
doaj   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Implementing a hospital-based case management intervention for people experiencing homelessness: the navigator program

BMC Health Services Research
Background People experiencing homelessness (PEH) have worse health than the general population, and higher rates of hospitalization. The transition period after discharge from hospital is often challenging for PEH, in part due to loss to follow-up ...
Jesse I. R. Jenkinson, Dinesh Moro, Oluwagbenga Dada, Kate Francombe Pridham, Jeremy Cygler, Stephen W. Hwang   +5 more
doaj   +1 more source

Impact of COVID-19 on the lives of people with severe mental illness—front-line community psychiatry workers observation from a provincial survey of assertive community treatment teams in Ontario, Canada

International Journal of Mental Health Systems, 2023
Using an online survey distributed to members of the provincial organization that represents the 88 Assertive Community Treatment (ACT) and Flexible ACT teams in Ontario, Canada, this descriptive study relied on the unique vantage points and observations
Aly Kassam, Michaela Beder, Saadia Sediqzadah, Matthew Levy, Madeleine Ritts, John Maher, Nicole Kirwan, Samuel Law   +7 more
doaj   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

The role of racial and socioeconomic status bias on medication prescribing practices: a qualitative study of family physician perspectives

BMC Primary Care
Background Physicians’ prescribing practices can be influenced by racial and socioeconomic status (SES) biases in a manner that impacts the well-being of patients. Little is known about this issue in the Canadian context.
Tadios Tibebu, Dylan Rose Balter, Stephen W. Hwang, Matthew To, Nav Persaud, Clara Juando-Prats, Jesse I. R. Jenkinson   +6 more
doaj   +1 more source

“We don't have a good system for people who don't have a home and don't need a hospital”: Contextualizing the hospital discharge process for people experiencing homelessness in Toronto, Canada

SSM: Qualitative Research in Health, 2022
Hospital discharge is a key transition in a patient's care pathway, providing an effective point of intervention to address a patient's ongoing health and social care needs. Addressing these needs may prevent hospital readmissions. The hospital discharge
Jesse I.R. Jenkinson, Stephen W. Hwang, Carol Strike, Erica Di Ruggiero   +3 more
doaj   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior, Edmara Bazoni Soares Maia, Soad Fuentes‐Alabí, Courtney E. Sullivan, Monnie Abraham, Mauricio Maza, Liliana Vásquez Ponce, Regina Aparecida Garcia Lima   +7 more
wiley   +1 more source

Identification of Confusable Herbal Medicines by Mapping of Partial Degradation Products from Herbal Medicine Polysaccharides

Analytical Sciences, 2018
Partial degradation products (PDPs) of herbal medicine (HM) polysaccharides with precolumn derivatization using 1-phenyl-3-methy-5-pyrazolone (PMP) were mapped by high performance liquid chromatography (HPLC), and three groups of confusable HMs were differentiated using the PDP fingerprints assisted with cluster analysis (CA).
Feifei, Yang, Huaizhong, Guo, Lisha, Zhang, Jing, Shi, Mengmeng, Shen, Dongqin, Han, Lixiao, Li   +6 more
openaire   +3 more sources