Results 81 to 90 of about 1,358,257 (368)

A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms.

New England Journal of Medicine, 2016
BACKGROUND Recent gains in reducing the global burden of malaria are threatened by the emergence of Plasmodium falciparum resistance to artemisinins. The discovery that mutations in portions of a P.
D. Ménard, N. Khim, J. Beghain, A. Adegnika, Mohammad Shafiul-Alam, O. Amodu, Ghulam Rahim-Awab, Celine Barnadas, A. Berry, Y. Boum, M. Bustos, Jun Cao, Jun-Hu Chen, L. Collet, L. Cui, G. Thakur, A. Dièye, D. Djallé, M. Dorkenoo, Carole E. Eboumbou-Moukoko, F. Espino, T. Fandeur, Maria-Fatima Ferreira-da-Cruz, A. Fola, H. Fuehrer, A. M. Hassan, S. Herrera, B. Hongvanthong, S. Houzé, M. Ibrahim, Mohammad Jahirul-Karim, Lubing Jiang, S. Kano, Wasif Ali-Khan, Maniphone Khanthavong, P. Kremsner, M. Lacerda, R. Leang, M. Leelawong, Mei Li, Khin Lin, J. Mazarati, Sandie Ménard, I. Morlais, Hypolite Muhindo-Mavoko, L. Musset, K. Na-Bangchang, Michael Nambozi, Karamoko Niaré, H. Noedl, J. Ouédraogo, D. Pillai, B. Pradines, Bui Quang-Phuc, M. Ramharter, M. Randrianarivelojosia, J. Sattabongkot, Abdiqani Sheikh-Omar, K. Silué, S. Sirima, C. Sutherland, D. Syafruddin, R. Tahar, Lin-hua Tang, O. Toure, Patrick Tshibangu-wa-Tshibangu, I. Vigan-Womas, M. Warsame, Lyndes Wini, S. Zakeri, Saorin Kim, Rotha Eam, L. Berne, Chanra Khean, Sophy Chy, Malen Ken, Kaknika Loch, L. Canier, V. Duru, E. Legrand, J. Barale, Barbara H. Stokes, J. Straimer, B. Witkowski, D. Fidock, C. Rogier, P. Ringwald, F. Ariey, O. Mercereau‐Puijalon   +88 more
semanticscholar   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Recent advances in understanding idiopathic pulmonary fibrosis [PDF]

, 2016
Despite major research efforts leading to the recent approval of pirfenidone and nintedanib, the dismal prognosis of idiopathic pulmonary fibrosis (IPF) remains unchanged.
Daccord, C, Maher, TM
core   +3 more sources

Substance use care innovations during COVID-19: barriers and facilitators to the provision of safer supply at a toronto COVID-19 isolation and recovery site

Harm Reduction Journal
Background Early in the COVID-19 pandemic, there was an urgent need to establish isolation spaces for people experiencing homelessness who were exposed to or had COVID-19.
Gillian Kolla, Chowdhury Nishwara Tarannum, Kaitlin Fajber, Fiqir Worku, Kris Norris, Cathy Long, Raphaela Fagundes, Anne Rucchetto, Eileen Hannan, Richard Kikot, Michelle Klaiman, Michelle Firestone, Ahmed Bayoumi, Gab Laurence, Kate Hayman   +14 more
doaj   +1 more source

The Diagnosis of Sulfated Hemoglobin (SulfHb) Secondary to Sulfur Dioxide Poisoning Using Matrix-Assisted Laser Desorption Time-of-Flight Mass Spectrometry (MALDI-ToF MS)—A Novel Approach to an Unusual Clinical Problem

Diagnostics, 2020
Sulfhemoglobinemia is a rare entity caused by irreversible sulfation of the heme moiety in haemoglobin to form sulfated haemoglobin (SulfHb) and has been caused by H2S arising from certain metabolites of drugs and bacterial infection.
Suzanne Docherty, Raminta Zmuidinaite, James Coulson, Martin Besser, Ray Iles   +4 more
doaj   +1 more source

A world map of esophagus cancer research: a critical accounting

Journal of Translational Medicine, 2019
Esophageal cancer (EC) is one of the deadliest cancers worldwide. The contemporary strong increase of the adenocarcinomas in Western countries and the high mortality rates require the intensification of prospective multinational studies.
D. Klingelhöfer, Yun Zhu, Markus Braun, D. Brüggmann, N. Schöffel, D. Groneberg   +5 more
semanticscholar   +1 more source

Pharmacogenomics and Personalized Medicine: Mapping of Future Value Creation [PDF]

BioTechniques, 2005
PERSONALIZED MEDICINE People have been talking about personalized medicine, to a point that it almost gets old. Some are firm believers in this revolution and are actively devoting effort to advance it, others wonder whether this is yet another hype, and yet many others may have an impression that, as promising a future as it paints, it may only become
Sean Xinghua Hu, Ann Kieffaber, Thomas Foster   +2 more
openaire   +4 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Nurses Alumni Association Bulletin, Fall 2001 [PDF]

, 2001
2001 - 2002 Meeting Date Calendar 2002 Annual Luncheon & Meeting Notice Bulletin Publication Committee, Officers and Committee Chairs The President\u27s Message Treasurer\u27s Financial Report Auditor\u27s Financial Report Alumni Scholarship Fund Resume ...
Caruso, Joan, Levine, Paula, Prisnock, Elizabeth K., Smith, Marian E., Wagner, John J., Wagner, Sally H.   +5 more
core   +2 more sources

Social, Clinical, and Behavioral Determinants of HIV Infection and HIV Testing among Black Men in Toronto, Ontario: A Classification and Regression Tree Analysis

Journal of the International Association of Providers of AIDS Care, 2020
Black men bear a disproportionate burden of HIV infection. These HIV inequities are influenced by intersecting social, clinical, and behavioral factors.
Pascal Djiadeu MSc, PhD, Martez D. R. Smith LMSW, Sameer Kushwaha MD, Apondi J. Odhiambo MPH, David Absalom MPH, Winston Husbands PhD, Wangari Tharao MEd, Rotrease Regan PhD, RN, MPH, Ting Sa MS, Nanhua Zhang PhD, Rupert Kaul MD, PhD, LaRon E. Nelson PhD, RN, FNP, FNAP, FAAN   +11 more
doaj   +1 more source