Results 121 to 130 of about 2,654,577 (297)
China 1:250,000 [cartographic material].
, 1955 Ed. 1 - AMS. "Constructed and molded in [year] from China 1:250,000 AMS Series L500; Each map is individually titled by area and numbered within the series.; Topographic raised relief model map series of China.
United States. Army Map Service
core
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
India and Pakistan 1:250,000 [cartographic material] /
, 1959 Various eds. Topographic map series of India and Pakistan showing populated places, railroads, boundaries and roads. Relief shown by contours and spot heights.
United States. Army Map Service.
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Manchuria 1:250,000 [cartographic material] /
, 1950 Various eds. "Constructed and molded in 1950 from Manchuria 1:250,000."; Each sheet is named and numbered individually.; Includes glossary and index to adjacent sheets.; Place names in Chinese and Wades Giles romanisation.; Topographic raised relief ...
United States. Army Map Service.
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Indochina 1:100,000 [cartographic material] /
, 1950 Various eds. Map series of Indochina showing roads, railways, canals, international and provincial boundaries, villages, churches, ruins, forest reserves, vegetation and cultivation. Relief shown by contours and spot heights.; "Copied ... from Carte de l'
United States. Army Map Service.
core
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Map of San Luis Obispo Co. California.
, 1910 Map shows early twentieth century San Luis Obispo County, California township grid, grants, roads, railroads, national forests, ranches, and telephone lines. Includes legend. Scale [1:253,440]
Progressive Map Service
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source