Results 121 to 130 of about 2,848,636 (250)
Whole-Brain Connectome Identifies PMv<sup>LepRb</sup> Neurons as a Hypothalamic Hub Linking Metabolic State to Instinctive Behavior. [PDF]
Zhang X, Dai Y, Shi Y, Yuan F.
europepmc +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Explicit correction of severely non-uniform distributions of cryo-EM views. [PDF]
Barchet C +4 more
europepmc +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Impacts of future sea level change on Greenland from community knowledge, coastal mapping, and glacial isostatic adjustment models. [PDF]
Tinto KJ +13 more
europepmc +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
A variational framework with composite sparse regularization for cryo-electron tomography reconstruction. [PDF]
Yu C +6 more
europepmc +1 more source
Some Equal-area, Conformal and Conventional Map Projections: A Tutorial Review
Ebrahim Ghaderpour
semanticscholar +1 more source

