Results 241 to 250 of about 2,506,502 (302)

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Single-cell reconstruction of whole-brain efferent projections from mouse ventral posteromedial thalamus. [PDF]

open access: yesBrain Inform
Wei HZ   +8 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Flex Projector - Interactive Program for Creating World Map Projections

open access: yesKartografija i Geoinformacije, 2009
Nedjeljko Frančula
doaj  

Searching for separation between frequency-modulated calls of blue and fin whales. [PDF]

open access: yesSci Rep
Wöhle S   +5 more
europepmc   +1 more source

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