Results 71 to 80 of about 2,848,636 (250)
Brain-wide map of efferent projections from rat barrel cortex
Frontiers in Neuroinformatics, 2014 The somatotopically organized whisker barrel field of the rat primary somatosensory (S1) cortex is a commonly used model system for anatomical and physiological investigations of sensory processing.
Izabela M. Zakiewicz +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Topography of the complete corticopontine projection: From experiments to principal maps
Frontiers in Neuroscience, 2007 The mammalian brain is characterized by orderly spatial distribution of its cellular components, commonly referred to as topographical organization.
Trygve B Leergaard, Jan G Bjaalie
doaj +1 more source
A Program for Handling Map Projections of Small Scale Geospatial Raster Data
, 2012 Scientists routinely accomplish small-scale geospatial modeling using raster datasets of global extent. Such use often requires the projection of global raster datasets onto a map or the reprojection from a given map projection associated with a dataset.
Michael P. Finn +5 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Interactive World Atlas - Exploration of the Potentials of Web Cartography
Kartografija i Geoinformacije, 2007 This paper describes a software configuration and data used for creating an interactive world atlas. Free software and data were chosen, and the potentials of such a choice are explored. The result is a simple interactive world atlas.
Dražen Tutić, Adriana Tanfara
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Map projections used by the U.S. Geological Survey
, 1982 After decades of using only one map projection, the Polyconic, for its napping program, the U.S. Geological Survey (USGS) now uses sixteen of the more common map projections for its published maps. For larger scale maps, including topographic quadrangles
J. Snyder
semanticscholar +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source