Results 131 to 140 of about 37,869 (277)
The Formulation and Review of Regulations Under the Food, Drug, and Cosmetic Act [PDF]
, 1939 Fuchs, Ralph F.
core +3 more sources
France Administrative : [mape aussé historique]
, 1870 Coordenadas : E6 20'-O5 00'/N56 55'-N42 25'. Meridiano de París Relieve : líneas perpendiculares normales Inserta mapa de Córcega Al márgen inferior izquierdo : Pous les détails orographiques voir la France Phisique de L ...
Bureau, E., Erhard, Lemercier
openaire +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Els mapes conceptuals per a la representació de la cultura moral dels centres educatius
Temps d'Educació, 2007 El presente artículo parte del supuesto de que la cultura moral de los centros educativos es uno de los principales agentes en la formación de sus miembros.
Laura Rubio i Serrano
doaj
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Kaotične jednodimenzionalne mape - usporedbe
, 2015 U radu su predstavljene četiri jednodimenzionalne kaotične mape: logistička, kubična, sinusna i „Symmetric tent mapa“. Prikazane su njihove karakteristike i ponašanje promjenom početnih uvjeta i kontrolnih parametara simulacijama u programu „Chaos for Java“.
openaire +1 more source