Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Empowering the biomedical research community: Innovative SAS deployment on the All of Us Researcher Workbench. [PDF]
Humes I +28 more
europepmc +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
The Use of Explainable Machine Learning for the Prediction of the Quality of Bulk-Tank Milk in Sheep and Goat Farms. [PDF]
Lianou DT +12 more
europepmc +1 more source
Clarel B. Mapes Receives Service Award
Mid Continent Oil and Gas Association. Clarel B. Mapes shown with silver tray presented him by state and local taxation committe for 25 years of service with the Mid Continent Oil and Gas Association.https://mavmatrix.uta.edu ...
core
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source
Prioritizing Data Quality in Machine Learning for Thermophysical Property Prediction: A Case Study on Normal Boiling Points of Organic Compounds. [PDF]
Mtetwa FT +3 more
europepmc +1 more source
Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
Sensors Network and Wearables for People Activities and Wellbeing Monitoring. [PDF]
Casaccia S, Cosoli G.
europepmc +1 more source

