Results 31 to 40 of about 8,279 (296)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
La Dialectometrització dels quatre primers volums de l'ALDC : una breu presentació
El present article representa un primer balanç de la dialectometrització del volums I-IV de l'Atles Lingüístic del Domini Català (ALDC) segons els principis teòrics i pràctics de l'«Escola Dialectomètrica de Salzburg» (EDMS).
Hans Goebl
doaj
Compared with traditional single-view and radiometric-only observations, multiangle polarimetric observations of water-leaving radiation play a crucial role in enhancing the retrieval of ocean constituents and aerosol microphysical properties.
Jia Liu +14 more
doaj +1 more source
Noves troballes dels gasteròpodes Aplus assimilis (Reeve, 1846) (F. Pisaniidae) i Mitrella psilla (Duclos, 1846) (F. Columbellidae) a la costa mediterrània espanyola Es donen a conèixer diverses troballes de dos gasteròpodes exòtics marins Aplus ...
A. Martínez-Ortí, A. Nappo, V. Escutia
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Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Es presenta un treball fet amb alumnes de primer de Batxillerat dins de l’assignatura Reptes Científics. L’objectiu principal és recollir dades a partir de les quals es generaran conclusions.
Judit Artigas Pursals
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Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
With predicted alterations in climate and land use, managing water resources is of the utmost importance, especially in areas such as the United States (U.S.) Coastal Plain where extensive connections exist between surface and groundwater systems.
Kerry L. Mapes, Narcisa G. Pricope
doaj +1 more source

