Results 81 to 90 of about 37,869 (277)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Creació d'un servidor de mapes OGC per a la consulta i publicació d'indicadors de l'Institut d'Estudis Regionals i Metropolitans de Barcelona (IERMB) [PDF]

, 2010
L'objectiu del projecte és la creació d'una proposta de servei d'Internet que proporcioni mapes temàtics per a la visualització i consulta de dades estadístiques territorials dels estudis i enquestes de l'Institut d'Estudis Regionals i Metropolitans de ...
Ambròs Albesa, Sònia, Nunes, Joan, Torres Querol, Albert, Universitat Autònoma de Barcelona. Facultat de Filosofia i Lletres   +3 more
core  

Geometria i mapes

, 2023
Aquest treball està enfocat a entendre millor els mapes, una eina que ens trobem en el nostre dia a dia i poques vegades ens parem a entendre com i perquè funcionen. En particular, ens focalitzarem en els mapes que busquen representar la Terra. Usant els coneixements de Geometria Diferencial veurem com aquesta ha ajudat al desenvolupament de la ...
openaire   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

ROLE OF THE FOOD DISTRIBUTION INDUSTRY IN CURRENT AND LONG RUN RESEARCH EFFORTS [PDF]

Marketing,
Krueckeberg, Harry F.
core   +1 more source

Diskretne kaotične mape

, 2023
The paper "Discrete Chaotic Maps" serves as an introduction to the study of discrete chaotic maps and the relevant background necessary for their understanding. The aim of the paper was to explore chaos theory and dynamical systems, as well as to examine the applications of these maps in various areas such as generating pseudo random numbers ...
openaire   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Análisis comparativo de editores de mapas conceptuales de uso libre

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2006
La digitalització de continguts a Internet troba en els mapes conceptuals una nova via de navegació semàntica en format hipertextual complementària del tipus de navegació que ofereixen els mapes de navegació convencionals.
Rovira, Cristòfol, Mesa Lao, Bartolomé
doaj