Results 241 to 250 of about 4,970,383 (343)

Outcomes of Focused Double Extrastimuli Mapping and Ablation in Ventricular Tachycardia. [PDF]

J Cardiovasc Electrophysiol
Jaroonpipatkul S, Keithler AN, Sathapanasiri T, Tandri H, Jared Bunch T, Ranjan R, Konstantinidis K.   +6 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Molecular mapping of flowering traits revealed a major QTL, qDFFF3.3.1 associated with early maturity in cucumber (Cucumis sativus L.). [PDF]

BMC Plant Biol
Pradeepkumara N, Parkash C, Dey SS, Bhatia R, Shekharappa N, Munshi AD, Behera TK, Bhattacharya RC, Talukdar A, Tomar BS.   +9 more
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Establishment of Machine Learning Models for Estimating the Collagen Content of Uterine Leiomyomas and Prediction of the Effect of Gonadotropin-Releasing Hormone Analog. [PDF]

Reprod Med Biol
Tamehisa T, Sato S, Tamura I, Tanabe M, Ito K, Sugino N.   +5 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Acoustic Quality Index evaluation: procedure improvement supported by the results of a subjective survey

Noise Mapping, 2017
Magrini Anna, Di Feo Gelsomina
doaj   +1 more source

Novel Application of an Imageless Robotic System in Revision Total Knee Arthroplasty: Unicompartmental Knee Arthroplasty Conversion, 1-Stage Revision, and 2nd-Stage Revision. [PDF]

Int J Med Robot
Tran JYS, Mak RW, Ho KK, Ng JP, Wong CK, Lam GY, Choi TL, Ong MT, Yung PS.   +8 more
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Cracking the code: AI's role in mapping evidence syntheses to the United Nations sustainable development goals. [PDF]

Arch Public Health
Pilla B, Stone J, Jordan Z.
europepmc   +1 more source