Results 161 to 170 of about 3,770,310 (253)

Long follow-up treating CHILD nevi with topical cholesterol and statins. [PDF]

An Bras Dermatol
Ferradoza MTN, Palhano ACM, Neumayer JMO, Samorano LP, Rivitti-Machado MC, de Oliveira ZNP.   +5 more
europepmc   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Excluding Ascites From the GEMA-Na Score Does Not Impact Outcome Predictions in Liver Transplant Candidates. [PDF]

Liver Int
Rodríguez-Perálvarez ML, Gómez-Orellana AM, Majumdar A, McCaughan GW, Kalafateli M, Taylor R, de la Rosa G, Aguilera MV, Gastaca M, Cepeda-Franco C, Ortiz ML, Colmenero J, Otero A, González Grande R, Cachero A, Molina Pérez E, Barreales M, Martín Mateos R, Rodríguez-Soler M, Romero M, Dopazo C, Alonso Martín C, Otón E, González Diéguez L, Espinosa MD, Arias Milla A, Blanco Fernández G, Lorente S, Cuadrado Lavín A, Sogbe M, Guijo-Rubio D, Hervás Martínez C, Tsochatzis E.   +32 more
europepmc   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Genetic patterns related to von Willebrand factor: implications on the need for mechanical ventilation, severity, and death in COVID-19. [PDF]

Front Med (Lausanne)
López Castro J, Diz-de Almeida S, López Reboiro ML, Sardiña González C, SCOURGE Cohort Group , Riancho JA, Rojas-Martinez A, Lapunzina P, Flores C, Cruz R, Carracedo A.   +10 more
europepmc   +1 more source

Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R‐Functionalized Magnetic Nanoparticles to Low‐Endocytic CCR9 Surface Receptors

Advanced Healthcare Materials, EarlyView.
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente, Isabel Corraliza‐Gorjón, Thomas S. van Zanten, María del Puerto Morales, Leonor Kremer, Domingo F. Barber   +5 more
wiley   +1 more source

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Correction to: Ambulatory bilateral groin hernia repair: open preperitoneal versus laparoscopic outcomes. [PDF]

Hernia
Gomez-Jurado MJ, Verdaguer-Tremolosa M, Rodrigues-Gonçalves V, Martínez-López P, Martínez-López M, Pera M, Dalmau M, López-Cano M.   +7 more
europepmc   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

[Planetary health: The inescapable role of family medicine]. [PDF]

Aten Primaria
Galindo Ortega G, Del Campo Giménez M, Gutiérrez Muñoz B, Navarro Beltrá M, Almécija Pérez MC.   +4 more
europepmc   +1 more source