Results 81 to 90 of about 3,770,310 (253)
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Entrevista con Charles Portilla Revollar
Charles Portilla ...
Ronald Delgado Morales +6 more
doaj
Immune complexes in chronic Chagas disease patients are formed by exovesicles from Trypanosoma cruzi carrying the conserved MASP N-terminal region [PDF]
The exovesicles (EVs) are involved in pathologic host-parasite immune associations and have been recently used as biomarkers for diagnosis of infectious diseases.
De Pablos, Luis Miguel +5 more
core +3 more sources
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Objective In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently, and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of the trajectory of a ...
Ji Soo Kim +18 more
wiley +1 more source
Synopsis of the genus Empicoris (Hemiptera: Heteroptera: Reduviidae) in Chile [PDF]
The species of Empicoris Wolff, 1811 recorded from Chile are listed, and an identification key for all four species is provided. New distributional records from Chile are added: E. errabundus (Say, 1832) and E.
Faundez, Eduardo Iván +1 more
core
Una conversación sobre arte contemporáneo y educación en contextos de salud con Josep Maria-Martin. Prototipo de espacio para la gestión de las emociones [PDF]
Conversation with Josep María MartínUna conversación sobre con Josep María ...
G. Cano, Marta
core +2 more sources
Objective Although treat‐to‐target urate‐lowering therapy (ULT) is endorsed as best practice in gout management, limited data exist on its impact on health‐related quality of life (HRQoL). We assessed the impact of treat‐to‐target ULT on HRQoL among participants receiving protocolized gout care, identifying factors associated with HRQoL and HRQoL ...
Austin Barry +16 more
wiley +1 more source
Objetivos: Evaluar características superficiales y estabilidad del color de compuestos de resina reforzados con circonio, producidos mediante impresión 3D, sustractiva y estratificada. Métodos: Discos (N=36) (Ø=10×1.0mm) se prepararon según tres grupos:
Luiza Freitas Brum Souza +7 more
doaj +1 more source
Objective Asymptomatic hyperuricemia is a precursor of gout and is also associated with cardiovascular disease and chronic kidney disease. The aim of this study was to understand perceptions about asymptomatic hyperuricemia and views about urate‐lowering therapy in people with asymptomatic hyperuricemia. Methods Participants in a multinational study of
Nicola Dalbeth +19 more
wiley +1 more source

