Results 121 to 130 of about 4,681,024 (311)

Fraseoloxía do mar na Mariña luguesa [PDF]

Cadernos de Fraseoloxía Galega, 2000
Monográfico. Primeiro número da colección “Cadernos de Fraseoloxía Galega” aberta para a exhumación de coleccións fraseolóxicas inéditas. É xa unha vella queixa que, tendo Galicia 1.195 quilómetros de costa e tendo levado a cabo no mar os galegos dende ...
Paco Rivas, Maite Veiga Díaz (coord.), Xesús Ferro Ruibal (dir.)   +2 more
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

FERTILITY CARE IN LOW- AND MIDDLE-INCOME COUNTRIES: Public sector access to medically assisted reproduction in South Africa: a case study

Reproduction and Fertility
In South Africa, approximately 10% of the calculated need for medically assisted reproduction is being met due to limited access and unequal availability of these services.
Gerhardus Marthinus Boshoff, Willem Ombelet, Carin Huyser   +2 more
doaj   +1 more source

Quick Reads, Mar 27, 2008 [PDF]

, 2008
IDPH Quick Reads is an electronic newsletter produced by the Director’s Office at the Iowa Department of Public Health.

core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Determinação de pontos no mar para apoio aos trabalhos da Petrobrás na plataforma continental

Revista Brasileira de Cartografia, 1984
n ...
Márcio Henrique O. de Aquino, Osmar Rocha Machado   +1 more
doaj  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Of Intellectual Property, Open Source and Innovation: Trends, and Some Opportunities for Italy [PDF]

This paper offers some reflections on the institutions for the governance of knowledge as an economic asset, and its management in firms. It then relies on a research based on a survey of a large number of patents (PatVal-EU) to discuss specific features
Alfonso Gambardella
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

An Equilibrium Model of Lumpy Housing Investment [PDF]

We formulate and solve a dynamic general equilibrium model with heterogeneous agents and lumpy housing adjustment at the household level. We use the model to ask a simple question: how does the microeconomic lumpiness of housing adjustment affect the ...
Marina Pavan, Matteo Iacoviello
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