Results 61 to 70 of about 335,867 (292)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Diario de un poeta recién casado: una obra maestra de un maestro

open access: yesMiscelánea Comillas, 2017
Queremos, en esta entrega, reflexionar sobre una obra que consagró definitivamente al nobel de Moguer. En Diario se marca un nuevo modo de hacer literatura, de tal forma que seguir escribiendo como antes de Diario quedaría obsoleto. La mezcla del verso y
Rosario Paniagua Fernández
doaj  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Peligros marítimos de marineros del norte de la corona de Castilla a finales de la Edad Media

open access: yesEdad Media, 2017
Este estudio se centra en los peligros a los que tuvieron que enfrentarse los marineros del Norte de Castilla, en especial, de San Vicente de la Barquera, Santander, Laredo y Castro Urdiales, cuatro villas portuarias que durante la Baja Edad Media fueron
Javier Añíbarro Rodríguez
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Entre tormentas, islas y piratas: el escenario marítimo en el libro de caballerías

open access: yesHistorias Fingidas, 2018
Este artículo tiene como objetivo mostrar un estudio del significado del escenario marino en el libro de caballerías castellano. Aparte, se analiza la importancia de los trayectos marítimos en las ficciones, la ausencia de una descripción realista y ...
Almudena Izquierdo Andreu
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Sea, Identity and Literature

open access: yes1616, 2013
The sea is more than water and remote horizons. Since the beginning of literatures, the sea has sent waves of challenges to human existence through numerous stories and poems and continues to do so in all media.
Svend Erik LARSEN
doaj  

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