Multiscale Approximations to Understand the Complex Role of Microglia in Alzheimer's Disease. [PDF]
Microglia are dynamic, context‐dependent regulators of Alzheimer's disease, modulating amyloid, tau, and neurodegeneration across disease stages. Integrating multiscale and human‐focused approaches is essential to translate microglial biology into therapeutic strategies. ABSTRACT Microglia, the resident innate immune cells of the central nervous system,
Martínez-Tazo P +9 more
europepmc +2 more sources
CSF Biomarker Profile of Cerebral Amyloid Angiopathy: Diagnostic Performance and Imaging Correlates in a Hospital-Based Neurology Cohort. [PDF]
Cerebral amyloid angiopathy (CAA) frequently coexists with Alzheimer's disease (AD), complicating diagnosis in patients with cognitive impairment. In this hospital‐based cohort including healthy controls, CAA, AD, and mixed CAA‐AD cases, CSF Aβ40 and Aβ42 provided complementary diagnostic value for identifying CAA. Lower CSF Aβ40 levels were associated
Fernández-Lebrero A +16 more
europepmc +2 more sources
Resting-state default mode network connectivity in young individuals with Down syndrome. [PDF]
DMN in Down syndrome. Network indicators in DS. Functional connectivity. Abstract Background Down syndrome (DS) is a chromosomal disorder that causes intellectual disability. Few studies have been conducted on functional connectivity using resting‐state fMRI (functional magnetic resonance imaging) signals or more specifically, on the relevant structure
Figueroa-Jimenez MD +6 more
europepmc +2 more sources
Relationship between locus coeruleus and slow-wave sleep in aging and Alzheimer's disease. [PDF]
Abstract INTRODUCTION Sleep disruption, particularly loss of slow‐wave sleep (SWS), is common in Alzheimer's disease (AD), but its neurobiological underpinnings remain unclear. We investigated whether locus coeruleus (LC) integrity relates to SWS across the AD continuum and whether sex and perivascular spaces (PVSs) modify these associations.
Falgàs N +20 more
europepmc +2 more sources
ChREBP-driven DNL and PNPLA3 Expression Induced by Liquid Fructose are Essential in the Production of Fatty Liver and Hypertriglyceridemia in a High-Fat Diet-Fed Rat Model. [PDF]
Rats receive a high fat diet with (HFHFr) and without liquid fructose (HFD). At the end of the experiment, body weight is unchanged, due to increased in thermogenesis. There are minor metabolic changes in livers from HFD‐fed rats, while HFHFr fed‐rats show liver steatosis and hypertriglyceridemia.
Velázquez AM +8 more
europepmc +2 more sources
Associations between air pollution and surrounding greenness with internalizing and externalizing behaviors among schoolchildren. [PDF]
Background Air pollution and greenness are emerging as modifiable risk and protective factors, respectively, in child psychopathology. However, research shows inconsistencies. Here, we examined associations between air pollution and surrounding greenness with internalizing and externalizing behaviors.
Zubizarreta-Arruti U +22 more
europepmc +2 more sources
Risk of cognitive decline progression is associated to increased blood-brain-barrier permeability: A longitudinal study in a memory unit clinical cohort. [PDF]
Abstract INTRODUCTION This study examined the relationship between blood‐brain‐barrier permeability (BBBp), measured by cerebrospinal fluid/serum albumin ratio (QAlb), and cognitive decline progression in a clinical cohort. METHODS This prospective observational study included 334 participants from the BIODEGMAR cohort.
Puig-Pijoan A +14 more
europepmc +2 more sources
Joan Maragall en l'obra de Joan Perucho
L’obra de Joan Perucho es caracteritza per una abundant transtextualitat amb la inclusió de nombroses referències i citacions de textos de tota mena, i de diversa procedència, no sempre literària.
Pere Torra
doaj +2 more sources
Ressenya de: Carles Riba i Joan Maragall, o la moral de la paraula, de Jaume Medina (Llengua Nacional, Cornellà, 2011, 265 pàgines).
Ramon Torné i Teixidó
exaly +3 more sources
Un himne franquista a l'Arxiu Joan Maragall
El músic i poeta Joan Llongueras i Badia (1880-1953) és conegut per ser l’introductor als Països Catalans del mètode Dalcroze d’ensenyança de música, que va tenir un gran impacte en el desenvolupament de l’estètica noucentista. Llongueras, doncs, fou un
Amadeu Corbera Jaume
doaj +1 more source

