Results 141 to 150 of about 2,059 (265)

End‐of‐Life Loneliness, Social Isolation, and Symptom Burden: A Nationally‐Representative Study

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Loneliness (subjective feeling of lacking connection) and social isolation (objective deficit in number of relationships or contact with others) are common at the end‐of‐life and can be detrimental to quality of life. Investigating the association between symptoms and end‐of‐life loneliness and social isolation could help inform ...
Mara Rosenberg   +3 more
wiley   +1 more source

Development of a Video‐Based Decision Aid for Breast Cancer Screening Among Older Women

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Whether to continue breast cancer screening beyond age 74 is uncertain. Decision aids may improve understanding of health information and support informed screening decisions. The goal of this study was to develop a video‐based decision aid for breast cancer screening among older women using patient‐centered design.
Meghan E. Lindsay   +6 more
wiley   +1 more source

Predictors of Cyclophosphamide Resistance in Granulomatosis with Polyangiitis: A Retrospective Cohort Study. [PDF]

open access: yesMediterr J Rheumatol
Dağlı PA   +14 more
europepmc   +1 more source

Constitution and function of intergenic genome regions in cultivated versus annual wild soybean in China

open access: yesJournal of Integrative Plant Biology, EarlyView.
Three‐case restricted two‐stage multi‐locus multi‐allele genome‐wide association study identified main‐effect genes and detected the regulatory effects of intergenic loci on genes, enabling comprehensive dissection of the genic‐intergenic genetic system for quantitative traits and providing a strategy for studying their genetic basis.
Xiaoshuai Hao   +11 more
wiley   +1 more source

Intermittent Fasting Ameliorates Testicular Damage via Oxidative Stress Modulation in a Genetic Absence Epilepsy Rat Model. [PDF]

open access: yesInt J Mol Sci
Gökçeoğlu Kayalı D   +9 more
europepmc   +1 more source

Disabling a conserved module confers broad‐spectrum resistance

open access: yesJournal of Integrative Plant Biology, EarlyView.
This commentary reviews the discovery by Yuan et al. of a conserved susceptibility module where fungal Gas2 stabilizes host SnRK1β1A to suppress nuclear immunity in rice. It discusses the mechanism for broad‐spectrum resistance via genome editing and considers the essential balance between enhanced defense and associated agronomic trade‐offs.
Zhen Zeng   +3 more
wiley   +1 more source

Chicken or egg? The evolutionary riddle of CMS and Rf in plants

open access: yesJournal of Integrative Plant Biology, EarlyView.
Cytoplasmic male sterility (CMS) reduces pollen fertility and nuclear Rf genes restore fertility. This Commentary explores support for the “arms race” and “pre‐adaptation” models for CMS–Rf co‐evolution. CMS and Rf interact dynamically, influencing plant reproduction, stress tolerance, and hybrid seed production, highlighting co‐evolutionary processes ...
Peilin Wang   +4 more
wiley   +1 more source

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