Results 31 to 40 of about 21,230 (262)

Methanotrophy under extreme alkalinity in a serpentinizing system

Nature Communications
Serpentinization produces hyperalkaline, H₂- and CH₄-rich fluids that support microbial life and serve as analogs for ocean worlds such as Enceladus. While methane production in these systems has been well studied, methane consumption—especially under ...
Alta E. G. Howells, Kirt Robinson, Miguel G. Silva, Ellen Cook, Lucas Fifer, Grayson Boyer, Tori Hoehler, Everett L. Shock   +7 more
doaj   +1 more source

A Study on Radiation Hazard of Granite and Marble Widely Used in Jordan Using Gamma Ray Spectrometer

Atom Indonesia, 2022
Granite and marble are widely used in building construction, so possible radioactive nuclides inside them may contribute to the exposure dose to human health. The purpose of this study was to investigate the natural radioactivity concentration and assess
A. N. Akour, S. Shakhatreh
doaj   +1 more source

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

Advanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong, Wenjun Zhou, Yuxiang Sun, Zihan Huang, Zhiyue Liu, Udhaya Kumar. S, Chenyan Li, Yi Lu, Chengchuang Song, Veronica C. Ciliberto, Makenna Mack, Lana E. Kim, Zhaoyong Hu, Fang Luo, Aihua Cao, Zheng Sun   +15 more
wiley   +1 more source

PBRM1 Deficiency in Microglia Leads to Excessive Neurogenesis and Autism‐Like Behaviors via the CCL5‐CCR1/5‐β‐catenin Signaling Axis

Advanced Science, EarlyView.
Microglial PBRM1 deficiency drives excessive hippocampal neurogenesis by enhancing CCL5–CCR1/5 signaling, leading to autism‐like behaviors. A pro‐inflammatory IL1α+/TNFα+ microglial subset is identified as a key cellular contributor to this process. PBRM1 represses Ccl5 expression at the transcriptional level.
Yang‐Yang Duan, Lin‐Fei Jiao, Pei‐Pei Liu, Chun‐Hui Duan, Xiao Li, Zi‐Han Zhang, Yue‐Qi Zhang, Xin‐Li Ouyang, Hong‐Zhen Du, Sha Liu, Yi Tang, Zhao‐Qian Teng, Chang‐Mei Liu   +12 more
wiley   +1 more source

Reimpiego e spolia nella tarda Antichità alla luce del materiale litico proveniente dal complesso archeologico di San Severo a Classe [PDF]

Studia Hercynia, 2019
The article aims to present results of the analysis of stone artefacts (fragments of architectural decoration, sarcophagi, opus sectile) from the late antique basilica and adjacent medieval monastery of San Severo in Classe (Ravenna, Italy).
Helena Tůmová , Enrico Cirelli
doaj  

Arhgef1 Deletion Disrupts Early Cortical Neurogenesis via PAK1 Overactivation and Causes Motor Dysfunction in Adulthood

Advanced Science, EarlyView.
ARHGEF1 plays a pivotal role in both embryonic cortical neurogenesis and adult motor function. During early development, it governs genesis of deep‐layer cortical neurons by negatively regulating RAC1/CDC42‐PAK1‐Cofilin signaling. In adulthood, ARHGEF1 is important for the maintenance of neuronal morphology and activity in the motor cortex, ensuring ...
Liuren Li, Xuanyue Ma, Zhenyu Ding, Bang Sun, Linglin Liu, Hei Matthew Yip, Wei Wang, Tianying Wu, Yuan Guo, Yinghui Peng, Shiqing Zhang, Jacque Pak Kan Ip, Li Zhang, Keshen Li, Lei Shi   +14 more
wiley   +1 more source

Canova's 'The Three Graces' [PDF]

Zbornik Radova Filozofskog Fakulteta u Prištini, 2009
Antonio Canova (1757-1822), the epitome of the neo-classical style, was born in a small village Passagno in the province of Treviso. At the age of fourteen he started learning sculpture in Venice; at first, he was placed under Giovanni Bernardi and ...
Marković Kamenko M.
doaj  

FRICTION COEFFICIENT OF RUBBER SLIDING AGAINST FLOORING MATERIALS [PDF]

Journal of the Egyptian Society of Tribology, 2011
The friction coefficient of rubber sliding against different types of flooring materials of different surface roughness was investigated under different sliding conditions: dry, water, water/detergent dilution, oil, water/oil dilution.
Y. M. El-Sherbiny, A. T. Hasouna, W. Y. Ali   +2 more
doaj   +1 more source

Early‐Life Polyethylene Microplastic Exposure Exacerbates ADHD‐Like Behaviors in Mice via PI3K/AKT1/Nrf2 Signaling: Evidence From the Pilot Cohort and Multi‐Omics Analyses

Advanced Science, EarlyView.
Circulating polyethylene microplastic burden is positively associated with heightened ADHD symptom severity and systemic redox‐inflammatory imbalance in children. Mechanistic investigation in a developmental co‐exposure mouse model further demonstrates that microplastics aggravate ADHD‐like behaviors, dopaminergic dysregulation, and oxidative ...
Yufan Luo, Ruijin Xie, Hua Xu, Xue Xiao, Wei Xiao, Qiyang Pan, Shengjie Xu, Li Liu, Zeliang Xiao, Yue Zhou, Chenyu Sun, Yu Wu, Yueying Liu   +12 more
wiley   +1 more source

Time Markers for SETI in Binary Systems: History and Prospects

Astronomy
Contemporary surveys in the search for extraterrestrial intelligence (SETI) typically make one-off “spot scans” across the sky to search planetary systems for narrow-band radio signals that would indicate the presence of intelligent life.
Jacob Haqq-Misra
doaj   +1 more source