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MARBURG-VIRUS DISEASE IN KENYA
The Lancet, 1982Abstract The third known outbreak of Marburg-virus disease occurred in Kenya in 1980. The index patient acquired infection in western Kenya, and a doctor in close contact with the patient terminally during a massive haematemesis developed infection in Nairobi. There was no further evidence of nosocomial transmission.
M. Isaacson +8 more
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Exploring plant-derived small molecules as inhibitors of Marburg virus RNA binding protein activity.
Journal of Biomolecular Structure and DynamicsThe search for antiviral medications is greatly influenced by the hunt for potent inhibitors of viral proteins. To find possible inhibitors of the RNA binding activity of the Marburg virus VP35 protein, we used a thorough in silico drug discovery ...
L. Bajrai +4 more
semanticscholar +1 more source
1971
The events and circumstances of the outbreak of Marburg virus disease in Germany and Yugoslavia during August and September, 1967, have been fully documented by a number of authors in the Deutsche Medizinische Wochenschrift, March 26, 1968, and in other publications [1, 2, 3].
H. Malherbe, M. Strickland-Cholmley
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The events and circumstances of the outbreak of Marburg virus disease in Germany and Yugoslavia during August and September, 1967, have been fully documented by a number of authors in the Deutsche Medizinische Wochenschrift, March 26, 1968, and in other publications [1, 2, 3].
H. Malherbe, M. Strickland-Cholmley
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Science Translational Medicine, 2022
Marburg virus (MARV) causes a severe hemorrhagic fever disease in primates with mortality rates in humans of up to 90%. MARV has been identified as a category A bioterrorism agent by the Centers for Disease Control and Prevention (CDC) and priority ...
Ruth Hunegnaw +18 more
semanticscholar +1 more source
Marburg virus (MARV) causes a severe hemorrhagic fever disease in primates with mortality rates in humans of up to 90%. MARV has been identified as a category A bioterrorism agent by the Centers for Disease Control and Prevention (CDC) and priority ...
Ruth Hunegnaw +18 more
semanticscholar +1 more source
1971
The pathological picture of Marburg-virus disease was described and discussed in the previous papers. Despite the obviously pantropic nature of the virus, damage to the liver was prevalent; therefore the histological features of the accompanying hepatitis are worth investigating. By comparing the findings in inoculated guinea pigs, the autopsies of the
H. Bechtelsheimer, P. Gedigk, G. Korb
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The pathological picture of Marburg-virus disease was described and discussed in the previous papers. Despite the obviously pantropic nature of the virus, damage to the liver was prevalent; therefore the histological features of the accompanying hepatitis are worth investigating. By comparing the findings in inoculated guinea pigs, the autopsies of the
H. Bechtelsheimer, P. Gedigk, G. Korb
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1980
Between 8 August and 10 September 1967, 30 cases of a previ- ously unknown and highly lethal disease occurred as an explo- sive epidemic which affected three locations in continental Europe: Marburg, Frankfurt and Belgrade. A thirty-first case occurred on 8 November.
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Between 8 August and 10 September 1967, 30 cases of a previ- ously unknown and highly lethal disease occurred as an explo- sive epidemic which affected three locations in continental Europe: Marburg, Frankfurt and Belgrade. A thirty-first case occurred on 8 November.
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The morphology and pathogenesis of “Marburg virus” hepatitis
Human Pathology, 1972Abstract The evolution of "Marburg virus" hepatitis is described on the basis of study of livers of experimentally infected guinea pigs and of patients who died or recovered from the disease. The first stage is characterized by disseminated single cell acidophilic necrosis of hepatocytes and Kupffer cell hyperactivity.
Gerhard Korb +2 more
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Marburg Virus Medical Countermeasures
Among the Filoviridae, Marburg virus (MARV) is a biological threat for which no licensed vaccines or therapeutics are currently available. In contrast, we have licensed products for Ebola virus (EBOV), another member of the Filoviridae family. The availability of licensed medical countermeasures (MCMs) for EBOV provides an opportunity to test a key ...Karen A, Martins, Daniel N, Wolfe
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Marburg Virus Minigenome Assays
This chapter describes minigenome systems for Marburg virus (MARV), which reconstitute the viral polymerase complex functions of gene expression and genome replication. Procedures covered herein include passage and seeding of cells, transfection, sample collection, and reporter gene assays.Ellen L, Suder +2 more
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