Results 21 to 30 of about 18,818 (71)

Non-invasive biomarkers of Fontan-associated liver disease

JHEP Reports, 2021
Background & Aims Fontan-associated liver disease (FALD) has emerged as an important morbidity following surgical palliation of single ventricle congenital heart disease. In this study, non-invasive biomarkers that may be associated with severity of FALD
J. Emamaullee, S. Khan, Carly Weaver, Cameron Goldbeck, G. Yanni, Rohit Kohli, Y. Genyk, Shengmei Zhou, Nick Shillingford, P. Sullivan, Cheryl M. Takao, J. Detterich, P. Kantor, J. Cleveland, C. Herrington, S. Ram Kumar, V. Starnes, S. Badran, N. Patel   +18 more
semanticscholar   +1 more source

Integrated Clinical and Magnetic Resonance Imaging Assessments Late After Fontan Operation.

Journal of the American College of Cardiology, 2021
BACKGROUND Several clinical and cardiac magnetic resonance (CMR)-derived parameters have been shown to be associated with death or heart transplant late after the Fontan operation.
Sophie L. Meyer, Nicole St. Clair, A. Powell, T. Geva, R. Rathod   +4 more
semanticscholar   +1 more source

Hepatorenal dysfunction assessment with the Model for End-Stage Liver Disease Excluding INR score predicts worse survival after heart transplant in pediatric Fontan patients.

Journal of Thoracic and Cardiovascular Surgery, 2021
BACKGROUND Fontan physiology results in multiorgan dysfunction, most notably affecting the liver and kidney. We evaluated the utility of Model for End-Stage Liver Disease Excluding INR (MELD-XI) score, a score evaluating the function of both liver and ...
S. Amdani, K. Simpson, P. Thrush, R. Shih, J. Simmonds, K. Knecht, D. Mogul, K. Hurley, D. Koehl, R. Cantor, D. Naftel, J. Kirklin, K. Daly   +12 more
semanticscholar   +1 more source

The “Super-Fontan” Phenotype: Characterizing Factors Associated With High Physical Performance

Frontiers in Cardiovascular Medicine, 2021
Background: People with a Fontan circulation usually have moderately impaired exercise performance, although a subset have high physical performance (“Super-Fontan”), which may represent a low-risk phenotype.
Derek L. Tran, D. Celermajer, J. Ayer, L. Grigg, C. Clendenning, T. Hornung, R. Justo, G. Davis, Y. D'udekem, R. Cordina   +9 more
semanticscholar   +1 more source

Associations Between Blood Biomarkers, Cardiac Function, and Adverse Outcome in a Young Fontan Cohort

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2021
Background Patients who have undergone the Fontan procedure are at high risk of circulatory failure. In an exploratory analysis we aimed to determine the prognostic value of blood biomarkers in a young cohort who have undergone the Fontan procedure ...
E. van den Bosch, S. Bossers, V. P. Kamphuis, E. Boersma, J. Roos‐Hesselink, J. Breur, A. D. ten Harkel, L. Kapusta, B. Bartelds, A. Roest, I. Kuipers, N. Blom, L. Koopman, W. Helbing   +13 more
semanticscholar   +1 more source

Physical exercise training in patients with a Fontan circulation: A systematic review.

European Journal of Preventive Cardiology, 2020
BACKGROUND Patients with a Fontan circulation have a reduced exercise capacity, which is an important prognostic predictor of morbidity and mortality. A way to increase exercise capacity in Fontan patients might be exercise training.
L. Scheffers, Linda Berg, G. Ismailova, K. Dulfer, J. Takkenberg, W. Helbing   +5 more
semanticscholar   +1 more source

DESCRIÇÃO DA TAXA DE RESERVA DE SANGUE E SUA UTILIZAÇÃO NAS CIRURGIAS PARA CORREÇÃO DE CARDIOPATIAS CONGÊNITAS EM MENORES DE 4 MESES

Hematology, Transfusion and Cell Therapy
Introdução: As cardiopatias congênitas ocorrem em 8-10 a cada 1000 nascidos vivos e, estão relacionadas a uma maior mortalidade entre lactentes. Elas podem ser classificadas em acianóticas e cianóticas dependendo do impacto no nível de oxigenação de ...
F Akil, GC Faria, RE Almeida, DNL Assis, VLR Pessoa, KA Mottta, VD Confort   +6 more
doaj   +1 more source

Hemodynamic and Clinical Implications of Impaired Pulmonary Vascular Reserve in the Fontan Circulation

Journal of the American College of Cardiology, 2020
Background: Pulmonary vascular disease, pulmonary endothelial dysfunction, liver fibrosis, renal disease, and exercise intolerance are common in adults with Fontan physiology.
A. Egbe, William R. Miranda, Jason H. Anderson, B. Borlaug   +3 more
semanticscholar   +1 more source

Body Composition in Young Adults Living With a Fontan Circulation: The Myopenic Profile

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2020
Background We sought to characterize body composition abnormalities in young patients living with a Fontan circulation and explore potential pathophysiologic associations.
Derek L. Tran, P. D'Ambrosio, C. Verrall, C. Attard, J. Briody, M. D'Souza, M. Fiatarone Singh, J. Ayer, Y. D'udekem, S. Twigg, G. Davis, D. Celermajer, R. Cordina   +12 more
semanticscholar   +1 more source

Severity of Fontan-Associated Liver Disease Correlates with Fontan Hemodynamics

Pediatric Cardiology, 2020
Fontan-palliated patients are at risk for the development of Fontan-associated liver disease (FALD). In this study, we performed a detailed hemodynamic and hepatic assessment to analyze the incidence and spectrum of FALD and its association with patients'
Anastasia Schleiger, M. Salzmann, P. Kramer, F. Danne, S. Schubert, C. Bassir, Tobias Müller, H. Müller, F. Berger, S. Ovroutski   +9 more
semanticscholar   +1 more source