Pharmacogenetic CYP2B6 variants affect steroid hormone metabolism in human breast cancer cells
Common genetic CYP2B6 variants correlate with adverse breast cancer outcome. The oestrogen metabolites estriol and 16‐epiestriol, which are formed downstream of CYP2B6‐catalysed 16α/β‐hydroxytestosterone, may be linked to elevated breast cancer risk and might increase due to the demonstrated CYP2B6 variants‐related metabolic shifts.
Marco Hoffmann +5 more
wiley +1 more source
Author Correction: Dolutegravir restores gut microbiota in late-stage HIV-1 unlike darunavir: an open-label, randomized clinical trial. [PDF]
Català-Moll F +16 more
europepmc +1 more source
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga +20 more
wiley +1 more source
The Complete Genome Sequences of Carludovica palmata Ruiz & Pavón and C. drudei Mast. [PDF]
Araujo-Sánchez JL +7 more
europepmc +1 more source
AI voice journaling for future language teachers: A path to well‐being through reflective practices
Abstract This study aimed to explore the perceived impact of using an AI‐powered voice journaling app in overcoming the challenges and stressors encountered by senior students enrolled in teaching practicum at an English Language Teaching Bachelor's programme.
Bora Demir, Duygu Özdemir
wiley +1 more source
For more Mangomoments in health care! [PDF]
Tartaglia A +3 more
europepmc +1 more source
Abstract Previous research concerning Global South doctoral students in the United Kingdom has mainly situated their experiences within adaptationist paradigms, emphasising cultural adjustment and assimilation into Western academic norms. Such studies often depict students as passive recipients, overlooking their agency and the transformative potential
Peng Zhang +3 more
wiley +1 more source
Real‐Time Biomass Estimation in High‐Density Yeast Fermentations Using Soft Sensor Modeling
Accurate biomass measurements, both offline and online, are essential to improve prediction and control in yeast fermentation. This study develops regression‐based predictive models to correlate offline measurements (Dry Cell Weight and OD600 from a spectrophotometer) with online OD860 probe signals to provide accurate real‐time biomass estimations and
Ana G. Del Hierro +3 more
wiley +1 more source
A Comparative Assessment of OECD Countries' Health Performance Through an Integrated Objective MCDM Framework. [PDF]
Kaya N +4 more
europepmc +1 more source
Extent, characteristics and policy applications of Key Biodiversity Areas
ABSTRACT A global standard for the identification of Key Biodiversity Areas (KBAs) was published 10 years ago to provide a unified set of criteria for identifying ‘sites of significance for the global persistence of biodiversity’. We review the initiative's origins, the KBA identification process, characteristics of the current network, threats, policy
Stuart H. M. Butchart +57 more
wiley +1 more source

