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APOE and genetic risk variants influence Alzheimer's disease onset in carriers of an extra copy of APP, with and without Down syndrome

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION An extra copy of the amyloid precursor protein (APP) gene causes autosomal dominant Alzheimer's disease (AD) and AD in Down syndrome (DS), but the factors underlying variability in age at onset (AAO) remain unclear. We investigated whether sporadic AD risk variants modify AAO. METHODS We analyzed clinical and genetic data from 100
Joan Groeneveld +39 more
wiley +1 more source

Sex Differences in Social, Health, and Lifestyle Characteristics Associated With Binge‐Eating Behaviors: Results From a French National Random Population‐Based Study

International Journal of Eating Disorders, Volume 59, Issue 8, Page 1814-1825, August 2026.
ABSTRACT Objective To explore sex differences in social, health and lifestyle characteristics associated with binge‐eating behaviors in a large population‐based study. Method This study included 84,995 participants (women 52.1%) aged ≥ 15 years from the French national random population‐based EpiCov cohort.
Junko Kose +21 more
wiley +1 more source

Decision aid reduces caregivers' preference for acid‐suppressive medication in infants with symptoms suggestive of reflux

Journal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 2, Page 258-264, August 2026.
Abstract Objectives Caregivers of infants with symptoms suggestive of gastroesophageal reflux (GER), such as regurgitation and excessive crying, often feel uncertain and seek treatment, though it is usually unnecessary. This study evaluated the effect of a decision aid on reducing caregivers’ preference for acid suppressive medication for infants ...
Anna de Geus +6 more
wiley +1 more source

Longitudinal Evaluation of Otoacoustic Emissions as a Screening Tool for High‐Frequency Hearing Loss in Adolescents

Otolaryngology–Head and Neck Surgery, Volume 175, Issue 2, Page 480-486, August 2026.
Abstract Objective To investigate the association between distortion product otoacoustic emission (DPOAE) signal‐to‐noise ratios (SNRs) and pure‐tone audiometry (PTA) thresholds in adolescents, both cross‐sectionally at age 18 and longitudinally by evaluating whether DPOAE SNRs at age 13 predict high‐frequency hearing loss (HFHL) at age 18.
Stefanie N. H. Reijers +5 more
wiley +1 more source

Exploring Consumers’ Acceptance, Emotions, and Attitudes Toward Clean Label Chocolates and/or Added Cocoa Shell

Journal of Food Science, Volume 91, Issue 8, August 2026.
ABSTRACT The influence of cocoa shells and/or the absence of additives in chocolates has not been deeply explored regarding consumers’ behaviors, and the present work provides essential information to help the food industry design strategies to produce healthy and sustainable products. The objective of the present work was to evaluate the impact of the
Fernanda Schiehll Azevedo +4 more
wiley +1 more source

The Opioid Safety Toolkit: An interactive prescription opioid safety toolkit to increase opioid safety literacy and behaviours among people prescribed opioids for pain—a randomised controlled trial

Addiction, Volume 121, Issue 8, Page 2071-2082, August 2026.
Abstract Background and aims Prescription opioid‐related harm remains a significant public health concern. This study aimed to evaluate the efficacy of the Opioid Safety Toolkit, a co‐designed, interactive online resource, in increasing naloxone uptake and healthcare provider discussions among adults prescribed opioids for pain.
Suzanne Nielsen +13 more
wiley +1 more source

SOCIETY NEWS

Brain Pathology, Volume 36, Issue 5, September 2026.
Audrey Rousseau
wiley +1 more source

Efficacy and safety of transcranial direct current stimulation in alcohol use disorder: A randomized controlled triple‐blind trial

Addiction, Volume 121, Issue 8, Page 2141-2153, August 2026.
Abstract Background and aims Current treatment options for alcohol use disorder are limited. Transcranial direct current stimulation has been proposed as a therapeutic approach, but evidence remains scarce. This study aimed to compare active vs. sham transcranial direct current stimulation to evaluate its efficacy and safety in reducing alcohol ...
Benoit Trojak +19 more
wiley +1 more source

International Guideline on the Diagnosis and Management of Pediatric Patients With Hereditary Angioedema

Allergy, Volume 81, Issue 8, Page 2744-2774, August 2026.
ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas +128 more
wiley +1 more source

The International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria

Allergy, Volume 81, Issue 8, Page 2582-2632, August 2026.
ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
Torsten Zuberbier +221 more
wiley +1 more source

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