Results 171 to 180 of about 486,062 (218)

Immune Responses to Marek’s Disease Virus Infection

2001
Marek’s disease (MD), a herpesvirus-induced lymphomatous disease in chickens, has attracted the interest of immunologists since MD virus (MDV) was isolated in 1968 and vaccines became available shortly afterwards (Witter 1985,Witter 2000). The pathogenesis of MD has been reviewed extensively (Calnek 1986,Calnek 1998,Calnek 2000; Schat 1987b). Infection
K A, Schat, C J, Markowski-Grimsrud
openaire   +2 more sources

T-cell transformation by Marek's disease virus

Trends in Microbiology, 1999
Marek's disease virus (MDV) is an avian herpesvirus that causes rapid development of T-cell lymphomas in chickens. The MDV genes currently thought to be involved in lymphomagenesis include a bZIP transactivator that is homologous to fos and jun oncogenes but do not appear to have counterparts in other oncogenic herpesviruses.
openaire   +2 more sources

Marek's Disease Virus-Induced Transient Cecal Tonsil Atrophy

Avian Diseases, 2014
Marek's disease (MD) is a lymphoproliferative disease of domestic chickens that is caused by a highly cell-associated oncogenic alpha-herpesvirus, Marek's disease virus (MDV). MDV replicates in chicken lymphocytes and establishes a latent infection within CD4+ T cells. MD is characterized by bursal and thymic atrophy and rapid onset of T cell lymphomas
Mohammad, Heidari, Scott D, Fitzgerald, Huanmin, Zhang   +2 more
openaire   +2 more sources

Effect of Phosphonoacetate on Marek's Disease Virus Replication

JNCI: Journal of the National Cancer Institute, 1976
Phosphonoacetate (PA), but not any of its analogues tested, effectively inhibited avian herpesvirus replication and viral DNA synthesis in cell cultures. At 100 mug/ml culture medium, PA completely inhibited the replication of Marek's disease virus (MDV), herpesvirus of turkeys, and owl herpesvirus, but had no measurable effect on normal cell growth ...
L F, Lee, K, Nazerian, S S, Leinbach, J M, Reno, J A, Boezi   +4 more
openaire   +2 more sources

Polyvalent Recombinant Marek’s Disease Virus Vaccine Against Poultry Diseases

2001
In 1982, Mackett et al. (1982) and Panicali and Paoletti (1982) constructed a recombinant vaccinia virus expressing a foreign gene, the thymidine kinase (TK) gene of herpes simplex virus (HSV), which was inserted into the nonessential regions of the virus genome by homologous recombination.
K, Hirai, M, Sakaguchi
openaire   +2 more sources

Partial restriction map of Marek's disease virus DNA

Gene, 1982
A partial restriction map of Marek's disease virus (MDV) DNA was constructed by digestion with endonucleases BamHI, Bg/I and SmaI and by blotting hybridization. The data suggest that there is a terminal heterogeneous sequence at least on one end of the MDV DNA molecule.
Y S, Lee, A, Tanaka, M, Nonoyama
openaire   +2 more sources

Current State of Marek's Disease Virus MicroRNA Research

Avian Diseases, 2013
MicroRNA (miRNA) is a major family of small RNAs that posttranscriptionally regulate gene expression. Small RNA profiling studies have revealed that some viruses, particularly large DNA viruses, such as Marek's disease virus (MDV), encode their own set of miRNAs. There are currently 406 viral miRNAs in miRBase, of which 392 are encoded by herpesviruses.
Julie A, Hicks, Hsiao-Ching, Liu
openaire   +2 more sources

Released and Extracted Virions of Marek's Disease Virus

Avian Diseases, 1973
SUMMARY A virus cloned from the pathogenic GA strain of Marek's disease virus (MDV) was propagated in duck embryo fibroblast culture. Virions released into the growth medium (RV) and virions extracted from the infected cells (EV) were separately concentrated, purified, and compared.
L F, Lee, K, Nazerian, H G, Purchase, B R, Burmester   +3 more
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Increased virulence of Marek's disease virus field isolates.

Avian diseases, 1997
R. Witter
semanticscholar   +1 more source

Cervical cancer prevention and control in women living with human immunodeficiency virus

Ca-A Cancer Journal for Clinicians, 2021
Philip E Castle, Vikrant V Sahasrabuddhe
exaly