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Hematopoietic Destruction in Marek's Disease

Avian Diseases, 1970
Hematopoietic destructive lesions, characterized by necrosis and loss of architecture in the bursa of Fabricius and thymus, were observed consistently in second-generation specific-pathogen-free X Line 7 (SPF X L7-F2) cross chickens inoculated at 1 day with an acute form of Marek's disease (MD) agent.
R M, Jakowski   +3 more
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Immunization against Marek's Disease

Avian Diseases, 1971
The turkey herpesvirus (HVT) and Marek's disease (MDHV) herpesvirus produce a similar virus-like cytopathic effect in monolayers of chick embryo fibroblasts. Discrete foci of rounded refractile cells and syncytial masses with some of the nuclei containing Cowdry type A inclusions were observed in affected monolayers.
C S, Eidson, D P, Anderson
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Genetic Resistance to Marek’s Disease

2001
Marek’s disease (MD) is economically one of the most significant diseases in chickens (Purchase 1985). It is of interest that numerous estimates of heritability of resistance to MD are relatively high compared to the resistance to other diseases in chickens or other diseases in domestic livestock.
L D, Bacon, H D, Hunt, H H, Cheng
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GENETIC RESISTANCE TO MAREK'S DISEASE*

Australian Veterinary Journal, 1976
A programme to control MD by genetic selection was tested by selecting breeding sires and dams whose progeny were found to have above average resistance to MD following inoculation at day old with infectious material. Under conditions of natural exposure, Australorp pullets from parents selected for resistance had a lower incidence of MD lesions than ...
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Immune mechanisms in marek's disease

Comparative Immunology, Microbiology and Infectious Diseases, 1979
Resistance to progressive tumor development in MD is either naturally inherited or can be induced by vaccination with apathogenic or attenuated MDV or with HVT. Studies on the effects of immunosuppression on resistance have shown that natural and vaccine induced resistance may be mediated through immune responses.
J M, Sharma, B R, Burmester
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Marek's Disease Virus Morphogenesis

Avian Diseases, 2013
Marek's disease virus (MDV) is a highly contagious virus that induces T-lymphoma in chicken. This viral infection still circulates in poultry flocks despite the use of vaccines. With the emergence of new virulent strains in the field over time, MDV remains a serious threat to the poultry industry.
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Marek's disease vaccination of chickens

Australian Veterinary Journal, 1996
Interpretive summaries of interesting articles on veterinary pharmacology are provided by the Pharmacology Chapter of the Australian College of Veterinary ...
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AUS in the Prevention of Marek's Disease

Avian Diseases, 1984
Aminoureidosulfone (AUS) was used as a feed additive to prevent mortality in Marek's disease (MD)-infected chickens in the laboratory. Chicks infected with MD virus (5000 plaque-forming units) at 1 day of age were given AUS in the feed from 1 day of age until the experiment was terminated.
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Marek’s Disease Virus Latency

2001
MDV latency is defined as the persistence of the viral genome in the absence of production of infectious virus except during reactivation. A number of systems for studying MDV latency exist, and most involve the use of lymphoblastoid cells or tumors. It has been difficult to divorce latency and transformation.
R W, Morgan   +6 more
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Latency and Tumorigenesis in Marek's Disease

Avian Diseases, 2013
Despite the remarkable progress in our understanding of Marek's disease (MD) and the causative Marek's disease virus (MDV) biology, a number of major features of this complex viral disease remain unknown. Significant information on critical aspects of virus latency in lymphoid cells, and the virus-host interaction in MDV-induced lymphoma, remains to be
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