Results 21 to 30 of about 35,038 (256)

No beneficial effect of general and specific anti-inflammatory therapies on aortic dilatation in Marfan mice. [PDF]

PLoS ONE, 2014
AIMS:Patients with Marfan syndrome have an increased risk of life-threatening aortic complications, mostly preceded by aortic dilatation. In the FBN1(C1039G/+) Marfan mouse model, losartan decreases aortic root dilatation.
Romy Franken, Stijntje Hibender, Alexander W den Hartog, Teodora Radonic, Carlie J M de Vries, Aeilko H Zwinderman, Maarten Groenink, Barbara J M Mulder, Vivian de Waard   +8 more
doaj   +1 more source

Generation of a human iPSC line QDMHi001-A from a patient with Marfan syndrome carrying a heterozygous c.6772 T > C variant in FBN1

Stem Cell Research, 2021
Variants in FBN1 are associated with Marfan Syndrome, an autosomal dominant disorder with clinical features that involve the musculoskeletal, cardiovascular and ocular systems. We generated a human iPSC line QDMHi001-A from a patient with Marfan syndrome
Suihan Wu, Zhendong Zhang, Lei Wang, Jin Yu   +3 more
doaj   +1 more source

Perspectives on the revised Ghent criteria for the diagnosis of Marfan syndrome [PDF]

, 2015
Three international nosologies have been proposed for the diagnosis of Marfan syndrome (MFS): the Berlin nosology in 1988; the Ghent nosology in 1996 (Ghent-1); and the revised Ghent nosology in 2010 (Ghent-2).
Bannas, Peter, Behzadi, Cyrus, Bernhardt, Alexander M, Blankenberg, Stefan, De Backer, Julie, Fuisting, Bettina, Hillebrand, Mathias, Kölbel, Tilo, Püschel, Klaus, Robinson, Peter N, Rybczynski, Meike, Schüler, Helke, Sheikhzadeh, Sara, von Kodolitsch, Yskert   +13 more
core   +2 more sources

Aortic Function in a Longitudinal 4D Flow MRI Study in Marfan Syndrome Patients Receiving Resveratrol. [PDF]

J Magn Reson Imaging
ABSTRACT Background New treatment strategies are required to reduce aortic events in Marfan syndrome (MFS). Resveratrol is a dietary supplement that intervenes in aortic wall cellular metabolism and may benefit MFS patients. Purpose To evaluate whether treatment with Resveratrol affects aorta hemodynamics derived from 4D flow MRI in MFS.
Bosshardt D, van Andel MM, Schrauben EM, van Kimmenade RRJ, Scholte AJ, Cox MGJP, Robbers-Visser D, Zwinderman AH, Mulder BJM, Nederveen AJ, de Waard V, Groenink M, van Ooij P.   +12 more
europepmc   +2 more sources

Pectus updates and special considerations in Marfan syndrome. [PDF]

, 2018
Congenital chest wall or pectus deformities including pectus excavatum (funnel chest) and pectus carinatum (pigeon chest) affect a significant proportion of the general population and up to 70% of patients with Marfan syndrome.
Child, A, Fraser, S, Hunt, I
core   +2 more sources

Diagnosis and Management of Marfan Syndrome

Majalah Kardiologi Indonesia, 2014
Background: Marfan syndrome is an autosomal dominant disorder of connective tissue, involving cardiovascular, ocular, skeletal and skin, pulmonary, and dura mater.
Andi Mahavira, Bambang B Siswanto
doaj   +1 more source

Biomechanical and biochemical properties of the thoracic aorta in warmblood horses, Friesian horses, and Friesians with aortic rupture [PDF]

, 2015
Background: Thoracic aortic rupture and aortopulmonary fistulation are rare conditions in horses. It mainly affects Friesian horses. Intrinsic differences in biomechanical properties of the aortic wall might predispose this breed.
Chiers, Koen, Claeys, Erik, Delesalle, Catherine, Ducatelle, Richard, Duchateau, Luc, Famaey, Nele, Gröne, Andrea, Ploeg, Margreet, Saey, Veronique, Smoljkic, Marija, van Loon, Gunther   +10 more
core   +2 more sources

High prevalence of ventricular repolarization abnormalities in people carrying TGFβR2 mutations

Scientific Reports, 2018
Mutations in the TGFβR2 gene have been associated with a life threatening risk of aortic dissection but no arrhythmic death has been previously reported.
F. Extramiana, O. Milleron, S. Elbitar, A. Uccellini, M. Langeois, M. Spentchian, G. Delorme, F. Arnoult, I. Denjoy, C. Bouleti, V. Fressart, F. Iserin, P. Maison-Blanche, M. Abifadel, A. Leenhardt, C. Boileau, G. Jondeau   +16 more
doaj   +1 more source

Twenty years' follow-up of a family with Marfan syndrome: A case series

Heart Views, 2021
Marfan syndrome is a rare connective tissue disorder manifesting with cardiovascular pathologies which are also the leading cause of death. Herein, we present the past 20 years follow up of a family with 17 members afflicted with Marfan syndrome.
Niloufar Valizadeh, Niloofar Rafatpanah, Farbod Hatami, Mohammad Hossein Davari, Toba Kazemi   +4 more
doaj   +1 more source

Gelatinolytic activity in gingival crevicular fluid and saliva of growing patients with Marfan syndrome: a case-control study

BMC Oral Health, 2019
Background Aim of the study was to evaluate the gelatinolytic activity in the saliva and gingival crevicular fluid from a sample group of subjects with Marfan syndrome. Methods Two groups were analyzed in this case-control study.
Giuseppina Laganà, Giovanni Francesco Fasciglione, Andrea Biondi, Massimiliano Coletta, Giovanni Ruvolo, Paola Cozza   +5 more
doaj   +1 more source