Results 41 to 50 of about 519,272 (217)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Pelayanan Misi Kontekstual Melalui Pendidikan Nilai Karakter Kristiani bagi Anak Jalanan di Kota Bandung

open access: yesDunamis: Jurnal Teologi dan Pendidikan Kristiani
. The 172 street children depicted are in vulnerable, marginal, and exploited conditions in the middle of the urban district of Bandung. To this day, the church as a spiritual institution and a community is still engaged in charitable diocese with a ...
Vicky Tainiady   +2 more
doaj   +1 more source

The films of Ciro Guerra and the making of cosmopolitan spaces in Colombian cinema

open access: yesAlphaville: Journal of Film and Screen Media, 2018
This article proposes to use the concept of “cosmopolitan cinematic margins” to analyse the paradoxical meeting of the cosmopolitan meaning and discourses of Ciro Guerra’s Colombian films and the spatial restrictions and immobility of the rural and ...
Maria Luna, Philippe Meers
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Novela Los dorados, de Sergio Muñoz: Jerarquización y exclusión en la sociedad costarricense

open access: yesRevista Humanidades, 2012
El texto de Sergio Muñoz devela una problemática socioeconómica del pueblo costarricense, la cual es palpable y visible. El aporte de su relato es que descarna a los personajes contando su historia de manera que supera la realidad con el diálogo que ...
María Eugenia Rojas Rodríguez
doaj  

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Análisis de la producción de café (Coffea arabica L.), en Amatepec, Estado de México

open access: yesEcosistemas y Recursos Agropecuarios
El municipio de Amatepec con una superficie plantada de 338 hectáreas es el principal productor de café en el Estado de México, con la participación de 230 productores tiene un volumen de producción de 393 toneladas.
Gabriel Leguizamo-Sotelo   +2 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy