Results 81 to 90 of about 115,593 (291)
Journal of Dental Sciences, 2020 The purpose of this study was to assess the clinical fit provided by EZIS system, the newly commercialized chairside CAD/CAM system. Prostheses were fabricated with the chairside CAD/CAM system (CS) and labside CAD/CAM system (LS) and marginal, axial ...
Jong-Ju Ahn +4 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Influência de diferentes métodos de captura de imagem na adaptação marginal e interna de restaurações cerâmicas fabricadas pelo sistema CAD/CAM - CEREC 3D: um estudo in vitro [PDF]
, 2012 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Odontologia, Florianópolis, 2010O objetivo desta pesquisa foi avaliar in vitro a influência de diferentes métodos de captura de imagem na
Delbons, Flávia Barros
core
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
An Application of Model-Fitting Procedures for Marginal Structural Models [PDF]
American Journal of Epidemiology, 2005 Marginal structural models (MSMs) are being used more frequently to obtain causal effect estimates in observational studies. Although the principal estimator of MSM coefficients has been the inverse probability of treatment weight (IPTW) estimator, there are few published examples that illustrate how to apply IPTW or discuss the impact of model ...
Kathleen M, Mortimer +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Avaliação da adaptação e infiltração marginal em restaurações cerâmicas (inlays): um estudo, in vitro [PDF]
, 2002 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Odontologia.Através deste estudo, in vitro, avaliou-se a adaptação e infiltração marginal gengival em inlays cerâmicos IPS Empress.
Pastre, Ruy
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Influência do desenho da cavidade na microinfiltração marginal de restaurações cerâmicas tipo MOD [PDF]
, 2006 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de de Pós-Graduação em Odontologia.O objetivo deste estudo foi avaliar a influência do desenho da cavidade na infiltração marginal de inlays cerâmicos ...
Kina, Mônica
core
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source