Results 51 to 60 of about 7,113,628 (317)

ULK4 and CDKN2A polymorphisms influence the risk of developing monoclonal gammopathy of undetermined significance

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor to multiple myeloma, sharing substantial genetic features with overt malignancy. Given evidence implicating autophagy in myeloma risk, this study examined whether genetic variations in autophagy‐related genes influence MGUS susceptibility.
José Manuel Sánchez‐Maldonado   +54 more
wiley   +1 more source

Zika Virus Infection, Philippines, 2012

open access: yesEmerging Infectious Diseases, 2015
To the Editor: Zika virus (ZIKV), a mosquitoborne flavivirus, was first isolated from a rhesus monkey in Uganda in 1947 (1). This positive-sense, single-stranded RNA virus (family Flaviviridae, genus Flavivirus) has a 10,794-nt genome and is most closely
M. T. Alera   +15 more
semanticscholar   +1 more source

Low‐value care and variation in practice in the care of children hospitalized with bronchiolitis in Canada (CareBEST): Protocol for a multi‐center prospective cohort study

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Introduction Low‐value care refers to health services for which the potential harms or costs outweigh the benefits of use. Bronchiolitis is the most common and among the most costly causes of pediatric hospitalizations. Evidence consistently shows that many common tests and treatments used to manage bronchiolitis do not improve outcomes ...
Branden Bonham   +39 more
wiley   +1 more source

Body composition analysis and handgrip strength as predictors of 12‐month mortality in hospitalized adults receiving parenteral nutrition: A descriptive cohort study

open access: yesJournal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Nutrition assessment in patients receiving parenteral nutrition often relies on classical parameters with limited prognostic value. Morphofunctional tools such as phase angle and handgrip strength measurement offer a more comprehensive evaluation of nutrition status and may better predict clinical outcomes. Objective To evaluate the
Natalia Montero Madrid   +13 more
wiley   +1 more source

Il metodo normale tra Prussia e Austria nel XVIII secolo

open access: yesStudi sulla Formazione
The article traces the origins of the normal method from Halle and Berlin to Sagan and then to Vienna, highlighting its Protestant matrix while also emphasizing the consistency with which Johann Felbiger applied it, adapting it to a Catholic population ...
Simonetta Polenghi
doaj   +1 more source

Association Between Colorectal Cancer Screening and Survival in Patients Older Than 70 Years: Results of A National Multicenter Retrospective Study

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background Colorectal cancer screening mainly targets a population between 50 and 70 years of age; however, it is inconsistently implemented in people over 70. The aim of this study was to analyze the association between colorectal cancer (CRC) screening, postoperative mortality, and perioperative and oncologic outcomes in a large population ...
Matteo Rottoli   +499 more
wiley   +1 more source

Long-term efficacy and safety of a tetravalent dengue vaccine (TAK-003): 4·5-year results from a phase 3, randomised, double-blind, placebo-controlled trial.

open access: yesLancet Global Health
BACKGROUND About half of the world's population lives in dengue-endemic areas. We aimed to evaluate the long-term efficacy and safety of two doses of the tetravalent dengue vaccine TAK-003 in preventing symptomatic dengue disease of any severity and due ...
Vianney Tricou   +31 more
semanticscholar   +1 more source

High Rate of Subclinical Chikungunya Virus Infection and Association of Neutralizing Antibody with Protection in a Prospective Cohort in The Philippines

open access: yesPLoS Neglected Tropical Diseases, 2015
Background Chikungunya virus (CHIKV) is a globally re-emerging arbovirus for which previous studies have indicated the majority of infections result in symptomatic febrile illness.
I. Yoon   +15 more
semanticscholar   +1 more source

'Entre todas as cidades, a cidade' de Mário Cláudio

open access: yesConvergência Lusíada, 2019
A cidade do Porto figura como eixo temático das obras de Mário Cláudio, fazendo-se presente, sobretudo,naquelas que percorrem o que aqui denominamos de percurso autobiográfico do escritor.
Mariana Caser da Costa
doaj   +1 more source

Genome‐Wide Assessment Reveals Ancestral Differences in Homozygosity Patterns Potentially Linked to Parkinson's Disease Etiology

open access: yesMovement Disorders, EarlyView.
Abstract Background Recessive genetic variation and extended runs of homozygosity (ROHs) may contribute to the unexplained heritability of Parkinson's disease (PD), particularly in diverse and understudied populations. Objective We conducted the first large‐scale, multi‐ancestral investigation of PD to examine the impact of genome‐wide homozygosity on ...
Kathryn Step   +680 more
wiley   +1 more source
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