Results 161 to 170 of about 657,593 (339)

Parent and peer pathways linking childhood experiences of abuse with marijuana use in adolescence and adulthood.

Addictive Behaviours, 2017
Alex M. Mason, M. Russo, M. B. Chmelka, R. C. Herrenkohl, Todd I. Herrenkohl   +4 more
semanticscholar   +1 more source

Assessing Major Adverse Liver Outcomes With Baclofen Compared to Acamprosate in Compensated Alcohol‐Associated Cirrhosis

Alimentary Pharmacology &Therapeutics, EarlyView.
We conducted a nationwide, multicenter cohort study using a target trial emulation framework to compare baclofen and acamprosate in patients with compensated alcohol‐associated cirrhosis. After matching, baclofen initiation was associated with a higher 1‐year risk of major adverse liver outcomes, driven primarily by hepatic encephalopathy, particularly
Yee Hui Yeo, Sepideh Mehravar, Ellen Choi, Ju Dong Yang, Hyun‐Seok Kim, Yun Wang, Aarshi Vipani, Hirsh D. Trivedi, Walid Ayoub, Parnian Naji, Alexander Kuo, Chun‐Ying Wu, Lorenzo Leggio, Juan Pablo Arab   +13 more
wiley   +1 more source

Effectiveness of School-Based Resilience Interventions on Adolescent Tobacco, Alcohol, and Illicit Substance Use: A Meta-Analysis. [PDF]

J Sch Health
ABSTRACT BackgroundResilience is a key protective factor in mitigating substance use behaviors in adolescence, but the effectiveness of school‐based resilience interventions remains unclear. MethodsRandomized and quasi‐experimental studies evaluating school‐based resilience interventions for tobacco, alcohol, or illicit substance use among students ...
Chae J, Kim H.
europepmc   +2 more sources

Characteristics of perinatal women seeking treatment for marijuana abuse in a community-based clinic

Archives of Women's Mental Health, 2013
Golfo K. Tzilos, Lynn A Hess, J. C. Kao, C. Zlotnick   +3 more
semanticscholar   +1 more source

The Australia story: Current status and future challenges for the clinical applications of psychedelics

British Journal of Pharmacology, EarlyView.
Abstract The past decade has seen a huge increase in clinical research with psychedelic drugs and 3,4‐methylenedioxymethamphetamine (MDMA), which have revealed great potential for treating mental health conditions. Given this progress in research, as well as the current unmet clinical need of millions of patients, in 2023, the Australian Therapeutic ...
David J Nutt, Peter Hunt, Anne Katrin Schlag, Paul Fitzgerald   +3 more
wiley   +1 more source

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source

A dimensional approach to understanding severity estimates and risk correlates of marijuana abuse and dependence in adults

International Journal of Methods in Psychiatric Research, 2012
Li-Tzy Wu, G. Woody, Chongming Yang, Jeng-Jong Pan, B. Reeve, D. Blazer   +5 more
semanticscholar   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Cumulative effect of multiple health and social factors on adolescent mental well‐being: a cross‐sectional study in Catalonia

Child and Adolescent Mental Health, EarlyView.
Background While numerous studies have explored factors contributing to poor mental health, few have examined the combined influence of multiple health and social factors and their cumulative effect. This study specifically aimed to analyze the cumulative effect of multiple health and social factors associated with poor mental well‐being in school‐aged
Marina Robles‐Muñoz, Marina Bosque‐Prous, Cinta Folch, Helena González‐Casals, Gemma Drou‐Roget, Cristina Torrado‐Cortés, Carles Muntaner, Albert Espelt   +7 more
wiley   +1 more source