Results 51 to 60 of about 657,593 (339)

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko, Titiaan E. Post, Pamela K. Strugala, Erica S. Klaassen, Linda E. Klumpers, Saco J. de Visser, Cristina Sempio, Jost Klawitter, Jules A. A. C. Heuberger, Geert J. Groeneveld   +9 more
wiley   +1 more source

Gonadal and Cortisol Hormone Profile among Male Chronic Khat, Marijuana, and Heroin Abuses

International Journal of Endocrinology, 2019
Background. Drugs of abuse could interfere with the hypothalamic-pituitary-gonadal axis, causing impaired functions of the gland and associated functions of target organs.
Meseret Yibrah, Abebe Edao Negesso, Atsbeha Gebregziabher, Feyissa Challa, Kissi Mudi, Feven Tesfay, Mehari Gebretsadkan, Samuel Kinde, Daniel Asmelash   +8 more
doaj   +1 more source

The grass is not always greener: a multi-institutional pilot study of marijuana use and acute pain management following traumatic injury

Patient Safety in Surgery, 2018
Background Widespread legislative efforts to legalize marijuana have increased the prevalence of marijuana use and abuse. The effects of marijuana on pain tolerance and analgesic pain management in the acute pain setting have not been reported.
Kristin Salottolo, Laura Peck, Allen Tanner II, Matthew M. Carrick, Robert Madayag, Emmett McGuire, David Bar-Or   +6 more
doaj   +1 more source

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

British Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou, Georgia Valsami, Georgios Ismailos   +2 more
wiley   +1 more source

Harmful alcohol use and frequent use of marijuana among lifetime problem gamblers and the prevalence of cross-addictive behaviour among Greenland Inuit: evidence from the cross-sectional Inuit health in transition Greenland survey 2006–2010 [PDF]

International Journal of Circumpolar Health, 2013
Background and objectives. Public health research has pointed to alcohol and substance abuse as the most significant public health challenges in Greenland with the negative impact on families and communities that entail, but few studies have investigated
Christina Viskum Lytken Larsen, Tine Curtis, Peter Bjerregaard   +2 more
doaj   +1 more source

Youth Marijuana and Prescription Drug Abuse in Anchorage [PDF]

, 2016
Complete issue of Alaska Justice Forum 33(1), Spring 2016 at https://scholarworks.alaska.edu/handle/11122/6883.This article examines results of the Adult Perceptions of Anchorage Youth: 2015 Survey (APAYS) to examine perceptions and concerns of Anchorage
Lepage, Cory R., Rivera, Marny
core  

Community pharmacists' practices and perspectives on deprescribing high‐risk psychotropic medicines: National survey findings

British Journal of Clinical Pharmacology, EarlyView.
Aim To explore the practices, confidence and perspectives of community pharmacists in deprescribing high‐risk psychotropic medicines, including opioid analgesics, benzodiazepine, gabapentinoids and medicinal cannabis. Methods An anonymous, cross‐sectional national online survey was conducted between January and April 2025 among Australian community ...
Monica Jung, Louisa Picco, Aili V. Langford, Rose Laing, Jana Dostal, Suzanne Nielsen   +5 more
wiley   +1 more source

Marijuana Use, Recent Marijuana Initiation, and Progression to Marijuana Use Disorder Among Young Male and Female Adolescents Aged 12-14 Living in US Households

Substance Abuse: Research and Treatment, 2017
Marijuana initiation during adolescence, and early adolescence in particular, is associated with adverse health consequences. Our study used 2005-2014 data from the annual, cross-sectional National Survey on Drug Use and Health to study the prevalence ...
Valerie L Forman-Hoffman, Cristie Glasheen, Kathryn R Batts   +2 more
doaj   +1 more source

Methamphetamine psychosis, the efficacy of atypical antipsychotics [PDF]

Reviews in Clinical Medicine, 2015
Worldwide growing methamphetamine abuse is one of the most serious health problems with several different consequences for victims, especially in developing countries.
Amir Rezaei Ardani, Azam Motamedi Nasab
doaj   +1 more source

Marijuana and e-cigarette use in a US national sample of 8th and 10th grade never-smokers of conventional cigarettes [PDF]

, 2018
Introduction: E-cigarette use remains a controversial topic in public health and medicine. Historically, cigarette smoking was identified as a gateway to marijuana use among adolescents.
Maslowsky, Julie, Owotomo, Olusegun
core   +2 more sources