Results 181 to 190 of about 493,280 (268)

“It's Not Deterministic and It Will Never Be Deterministic”: A Qualitative Study on Stakeholder Perspectives of Polygenic Risk Score Testing for Post‐Traumatic Stress Disorder

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Post‐traumatic stress disorder (PTSD) causes significant mental and physical distress, yet only a small subset of individuals exposed to trauma develop the disorder. Scientists and clinicians are still unable to predict who will get the disorder or how it will manifest.
Brandy M. Fox
wiley   +1 more source

A Wagner–Meerwein‐Like Rearrangement Generates a Vinyl Group in the Biosynthesis of the Polychlorinated Lipopeptides Fischerazoles

Angewandte Chemie, EarlyView.
The fischerazoles, unusual cyanobacterial chlorinated lipopeptides are reported. During their biosynthesis, a linear fatty acyl‐acyl carrier protein (ACP) precursor is rearranged through the action of the S‐adenosyl‐methionine (SAM)‐dependent methyltransferase FshF, to generate a pendant vinyl group.
Sandra A. C. Figueiredo, Kathleen Abt, Konrad Viehrig, Peter J. Jervis, Teresa P. Martins, Iñaki Lacomba, Chuhan Li, Daniele Castagnolo, Pedro N. Leão   +8 more
wiley   +2 more sources

Dialogue, inclusion, and adaptation in a remote marine sanctuary: evidence from Flower Garden Banks. [PDF]

Environ Manage
Dunning KH, Morris D, Bowles N, Camus C, Castruccio F, Cherian D, Cole D, Collins J, Furland T, Kleypas J, Krumhardt K, Luchauer G, Miranda Paez A, Moulton M, Wheeler I, Willoughby JR.   +15 more
europepmc   +1 more source

Spinal Involvement in a Pediatric and Adult Cohort of Patients With Arthrogryposis Multiplex Congenita

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT This was a single‐center retrospective observational study with national recruitment from October 2007 to March 2022 at the AMC clinic of the University Hospital Grenoble Alpes (CHUGA). Participants underwent a clinical spinal assessment and spine radiography.
Alicia Mom, Véronique Bourg, Shenhao Dai, Alicia‐Marine Milot, Dominic Perennou, Klaus Dieterich   +5 more
wiley   +1 more source

Open-access marine biodiversity records from the Colombia BIO Juradó-Cupica Expedition, Northern Colombian Pacific. [PDF]

Biodivers Data J
Dorado-Roncancio EF, Montoya-Cadavid E, Rodríguez-Toscano AJ, López de Mesa LÁ, Chasqui L, Londoño-Cruz E, Bechara-Escudero RM, Cedeño-Posso CM, Barrios-Vásquez E, Atencia-Galindo M, Yepes-Narvaez V, Rodríguez-Sánchez A, Sánchez Muñoz JV, Lizarazo N, Ossa-Hernandez N, Gallego-Sánchez DV, Restrepo V, Orozco Llanos V, Gomez-Vanega HD, Pardo Rivera AP, González Carreño LS, Ortega Sánchez CD, Osorno-Arango A, Coneo-Gómez S, Cera Marulanda LF, Mercado-Vides JJ, Murillo Jiménez KS, Monge López HM, Zea S, Tavera J, Beltran-Leon BS, Murillo Posso YC, Vides Casado MP, Alonso Carvajal DA.   +33 more
europepmc   +1 more source

Evolutionäre, funktionelle und mechanistische Charakterisierung mikrobieller Terpensynthase‐ähnlicher Gene aus Springschwänzen

Angewandte Chemie, EarlyView.
Eine Genomanalyse zeigte das Vorkommen zahlreicher Terpensynthasen des bakteriellen Typs in Springschwänzen. Vier Enzyme aus Sinella curviseta wurden funktionell charakterisiert, was zur Isolierung mehrerer Verbindungen führte, darunter Sinellenether, der erste identifizierte Diterpenether einer Terpensynthase mit einem neuartigen Grundgerüst.
Min Wang, Clement Schneider, Zarley Rebholz, Stefan Schulz, Kathy Darragh, Jeroen S. Dickschat   +5 more
wiley   +1 more source

Rise of modern marine fishes captured in an early Paleocene Lagerstätte. [PDF]

Sci Adv
El-Sayed S, Friedman M, Salem BS, Gohar AS, Al-Ashqar SF, Amin M, El-Saka H, Saad H, Speijer RP, Sallam HM.   +9 more
europepmc   +1 more source

Defragmenting Mangrove Law Towards Coherent Global Governance. [PDF]

Ecol Evol
Lorber M, Cappa P.
europepmc   +1 more source

Synthese und aktivitätsbasierte Proteinprofilierung identifizieren die Aldo‐Keto‐Reduktase 1C3 als Zielprotein der Myxoglucamide

Angewandte Chemie, EarlyView.
Myxoglucamid A – ein neuartiges, aus Myxobakterien isoliertes Glykolipopeptid – wurde erstmals totalsynthetisch hergestellt. Mittels aktivitätsbasierter Proteinprofilierung (ABPP) wurde die Aldo‐Keto‐Reduktase 1C3 (AKR1C3) als primäres Zielprotein in menschlichen Zellen identifiziert.
Thomas Siemon, Vivek K. Mishra, Mingming Zhao, Konrad Büssow, Alexander Popoff, Chengzhang Fu, Rolf Müller, Lothar Jänsch, Wulf Blankenfeldt, Mark Brönstrup   +9 more
wiley   +1 more source

Tracking rehabilitated sea turtles in the Indian Ocean using satellite telemetry: Insights into behaviour, ecology, and conservation implications. [PDF]

PLoS One
Himpson K, Le Berre T, Hodges E.
europepmc   +1 more source